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Catalog Number:
38195
CAS Number:
29868-97-1
Pirenzepine dihydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride
Documents
$51.18 /200MG
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Product Information

Pirenzepine dihydrochloride is a potent muscarinic antagonist primarily utilized in the treatment of peptic ulcers and gastrointestinal disorders. This compound exhibits selective inhibition of the M1 muscarinic receptor, making it particularly effective in reducing gastric acid secretion and promoting mucosal healing. Its unique mechanism of action allows for targeted therapeutic effects, distinguishing it from other anticholinergic agents. Researchers and healthcare professionals appreciate Pirenzepine dihydrochloride for its ability to minimize side effects commonly associated with broader-spectrum anticholinergics, thus enhancing patient compliance.

In addition to its clinical applications, Pirenzepine dihydrochloride is also of interest in pharmacological research, particularly in studies exploring the role of muscarinic receptors in various physiological processes. Its potential use in treating conditions such as irritable bowel syndrome and other gastrointestinal motility disorders further underscores its versatility. With ongoing research, the compound holds promise for expanding its therapeutic applications, making it a valuable addition to any pharmaceutical portfolio.

Synonyms
5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride
CAS Number
29868-97-1
Purity
≥ 98% (HPLC)
Molecular Formula
C19H21N5O2·2HCl
Molecular Weight
424.33
MDL Number
MFCD00055214
PubChem ID
71405
Melting Point
269 - 271 °C (dec.)
Appearance
White to yellow to orange powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride
CAS Number
29868-97-1
Purity
≥ 98% (HPLC)
Molecular Formula
C19H21N5O2·2HCl
Molecular Weight
424.33
MDL Number
MFCD00055214
PubChem ID
71405
Melting Point
269 - 271 °C (dec.)
Appearance
White to yellow to orange powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pirenzepine dihydrochloride is widely utilized in research focused on:

  • Gastroenterology: This compound is primarily used to treat peptic ulcers by reducing gastric acid secretion, making it valuable in clinical settings for managing ulcer-related conditions.
  • Pharmacological Studies: Researchers employ pirenzepine to study its effects on muscarinic receptors, aiding in the development of new drugs targeting similar pathways in various diseases.
  • Neurological Research: Its role as a selective M1 muscarinic receptor antagonist allows scientists to explore potential treatments for cognitive disorders, including Alzheimer's disease.
  • Drug Development: The compound serves as a lead structure in medicinal chemistry, inspiring the design of novel therapeutics with improved efficacy and reduced side effects.
  • Clinical Trials: Pirenzepine is often included in trials to assess its effectiveness in combination therapies, providing insights into multi-drug regimens for gastrointestinal disorders.

Citations