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Catalog Number:
38190
CAS Number:
34183-22-7
Propafenone hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanonehydrochloride
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Product Information

Propafenone hydrochloride is a potent antiarrhythmic agent primarily used in the management of various cardiac arrhythmias. This compound functions by stabilizing cardiac membranes and modulating ion channel activity, making it effective in treating conditions such as atrial fibrillation and ventricular tachycardia. Its unique dual action as both a sodium channel blocker and a beta-adrenergic antagonist allows for a comprehensive approach to rhythm control, providing significant benefits over traditional therapies.

In clinical settings, Propafenone hydrochloride is often favored for its oral bioavailability and rapid onset of action, making it suitable for both acute and chronic management of arrhythmias. Researchers and healthcare professionals appreciate its versatility, as it can be used in combination with other antiarrhythmic drugs to enhance therapeutic outcomes. The compound's favorable pharmacokinetic profile and efficacy in restoring normal heart rhythm underscore its importance in cardiology, offering patients a reliable option for managing their heart health.

Synonyms
1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanonehydrochloride
CAS Number
34183-22-7
Purity
≥ 98% (HPLC)
Molecular Formula
C21H27NO3·HCl
Molecular Weight
377.91
MDL Number
MFCD00079243
PubChem ID
36708
Melting Point
171 - 175 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanonehydrochloride
CAS Number
34183-22-7
Purity
≥ 98% (HPLC)
Molecular Formula
C21H27NO3·HCl
Molecular Weight
377.91
MDL Number
MFCD00079243
PubChem ID
36708
Melting Point
171 - 175 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Propafenone hydrochloride is widely utilized in research focused on

  • Cardiology: This compound is primarily used as an antiarrhythmic medication to treat irregular heartbeats, providing significant benefits for patients with atrial fibrillation or ventricular tachycardia.
  • Pharmaceutical Development: Researchers use propafenone hydrochloride in drug formulation studies to explore its efficacy and safety profiles, aiding in the development of new cardiovascular therapies.
  • Clinical Trials: It plays a crucial role in clinical trials aimed at assessing the effectiveness of heart rhythm control medications, helping to establish guidelines for patient care.
  • Drug Interaction Studies: The compound is essential in studying drug interactions, particularly with other cardiovascular drugs, to ensure safe and effective treatment regimens for patients.
  • Research on Metabolism: Propafenone hydrochloride is used in pharmacokinetic studies to understand how the body metabolizes antiarrhythmic drugs, which can lead to improved dosing strategies and patient outcomes.

Citations