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Catalog Number:
38181
CAS Number:
191217-81-9
Pramipexole dihydrochloride monohydrate
Purity:
≥ 98% (HPLC)
Synonym(s):
(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazoledihydrochloride monohydrate, PPX dihydrochloride monohydrate
Documents
$29.34 /100MG
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Product Information

Pramipexole dihydrochloride monohydrate is a potent dopamine agonist primarily used in the treatment of Parkinson's disease and restless legs syndrome. This compound acts by stimulating dopamine receptors in the brain, which helps to alleviate the symptoms associated with these neurological disorders. Its unique structure allows for effective penetration of the blood-brain barrier, making it a valuable therapeutic agent in managing motor control and reducing discomfort in patients.

In addition to its established medical applications, pramipexole dihydrochloride monohydrate is also being explored for potential uses in other neurological conditions, showcasing its versatility in research settings. Its favorable pharmacokinetic profile and relatively low side effect profile compared to other dopamine agonists make it a preferred choice among healthcare professionals. Researchers and industry professionals can leverage this compound for innovative studies aimed at understanding and treating various dopamine-related disorders, thus enhancing patient care and therapeutic outcomes.

Synonyms
(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazoledihydrochloride monohydrate, PPX dihydrochloride monohydrate
CAS Number
191217-81-9
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17N3S·2HCl·H2O
Molecular Weight
302.26
MDL Number
MFCD02183927
PubChem ID
22726023
Melting Point
290 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = -65 to -71 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazoledihydrochloride monohydrate, PPX dihydrochloride monohydrate
CAS Number
191217-81-9
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17N3S·2HCl·H2O
Molecular Weight
302.26
MDL Number
MFCD02183927
PubChem ID
22726023
Melting Point
290 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = -65 to -71 ° (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pramipexole dihydrochloride monohydrate is widely utilized in research focused on:

  • Treatment of Parkinson's Disease: This compound is primarily used in the management of Parkinson's disease, helping to alleviate symptoms such as tremors and stiffness, thereby improving the quality of life for patients.
  • Restless Legs Syndrome (RLS): It is effective in treating RLS, providing relief from uncomfortable sensations in the legs, which can disrupt sleep and daily activities.
  • Neuroprotective Research: Researchers explore its neuroprotective properties, investigating its potential to protect neurons from damage, which could lead to advancements in treating neurodegenerative disorders.
  • Clinical Trials: The compound is frequently involved in clinical trials aimed at discovering new therapeutic uses, enhancing its role in pharmaceutical development.
  • Combination Therapies: It is often studied in combination with other medications to assess synergistic effects, potentially leading to more effective treatment regimens for various neurological conditions.

Citations