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Catalog Number:
38169
CAS Number:
915967-82-7
Piperaquine tetraphosphate tetrahydrate
Purity:
≥ 98% (HPLC)
Synonym(s):
1,3-Bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propanetetraphosphate tetrahydrate, 7-Chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
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Product Information

Piperaquine tetraphosphate tetrahydrate is a potent antimalarial compound known for its effectiveness in treating malaria, particularly in combination therapies with artemisinin derivatives. This compound is characterized by its unique structure, which enhances its pharmacological properties, making it a valuable asset in the fight against malaria. Its high solubility and stability in aqueous solutions allow for easy formulation into various dosage forms, including tablets and injectable solutions, which are crucial for patient compliance and treatment efficacy.

In addition to its primary use in malaria treatment, Piperaquine tetraphosphate tetrahydrate shows promise in research settings, particularly in the development of new antimalarial therapies and drug resistance studies. Its ability to target multiple stages of the malaria parasite lifecycle makes it a versatile candidate for further exploration in pharmaceutical applications. Researchers and industry professionals can leverage its unique properties to develop innovative solutions for malaria management, ultimately contributing to global health initiatives.

Synonyms
1,3-Bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propanetetraphosphate tetrahydrate, 7-Chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
CAS Number
915967-82-7
Purity
≥ 98% (HPLC)
Molecular Formula
C29H32Cl2N6·4H3PO4·4H2O
Molecular Weight
999.55
MDL Number
MFCD11870901
PubChem ID
49849842
Melting Point
252 °C (dec.)
Appearance
White to orange to green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1,3-Bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propanetetraphosphate tetrahydrate, 7-Chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline
CAS Number
915967-82-7
Purity
≥ 98% (HPLC)
Molecular Formula
C29H32Cl2N6·4H3PO4·4H2O
Molecular Weight
999.55
MDL Number
MFCD11870901
PubChem ID
49849842
Melting Point
252 °C (dec.)
Appearance
White to orange to green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Piperaquine tetraphosphate tetrahydrate is widely utilized in research focused on:

  • Antimalarial Treatments: This compound is primarily used in combination therapies for malaria, enhancing the efficacy of existing treatments and helping to combat drug resistance.
  • Pharmaceutical Development: It serves as a key ingredient in the formulation of new antimalarial drugs, allowing researchers to explore its synergistic effects with other compounds.
  • Clinical Research: Piperaquine tetraphosphate tetrahydrate is involved in clinical trials aimed at evaluating its safety and effectiveness in various populations, providing valuable data for healthcare professionals.
  • Vector Control Studies: The compound is also studied for its potential in controlling malaria vectors, contributing to broader public health strategies aimed at reducing malaria transmission.
  • Drug Formulation Innovations: Its unique properties facilitate the development of advanced drug delivery systems, improving the bioavailability and therapeutic outcomes of antimalarial medications.

Citations