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Catalog Number:
38168
CAS Number:
65-28-1
Phentolamine mesylate
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazolinemethanesulfonate, Phentolamine methanesulfonate
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$66.80 /100MG
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Product Information

Phentolamine mesylate is a potent non-selective alpha-adrenergic antagonist widely utilized in both clinical and research settings. This compound is primarily known for its role in managing hypertensive crises and as a diagnostic tool in pheochromocytoma. Its unique ability to block alpha-adrenergic receptors makes it invaluable in various medical applications, including the treatment of erectile dysfunction and the reversal of local anesthesia in dental procedures. Researchers also explore its potential in studying cardiovascular responses and its effects on blood pressure regulation, making it a versatile agent in pharmacological studies.

In addition to its therapeutic uses, phentolamine mesylate is recognized for its rapid onset of action and relatively short duration, allowing for precise control in acute situations. Its effectiveness in promoting vasodilation and improving blood flow highlights its significance in both clinical and experimental pharmacology. With ongoing research into its broader applications, phentolamine mesylate remains a critical compound for professionals seeking reliable solutions in cardiovascular health and beyond.

Synonyms
2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazolinemethanesulfonate, Phentolamine methanesulfonate
CAS Number
65-28-1
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C17H19N3O·CH4O3S
Molecular Weight
377.46
MDL Number
MFCD00134201
PubChem ID
91430
Melting Point
178 - 182 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazolinemethanesulfonate, Phentolamine methanesulfonate
CAS Number
65-28-1
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C17H19N3O·CH4O3S
Molecular Weight
377.46
MDL Number
MFCD00134201
PubChem ID
91430
Melting Point
178 - 182 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phentolamine mesylate is widely utilized in research focused on:

  • Medical Applications: It is primarily used in the treatment of hypertension and to manage complications arising from pheochromocytoma, a tumor of the adrenal gland that can cause high blood pressure.
  • Dental Procedures: This compound is often employed as a local anesthetic to reverse the effects of anesthesia in dental surgeries, allowing patients to regain sensation more quickly.
  • Research in Cardiovascular Studies: Researchers use phentolamine mesylate to study its effects on blood pressure regulation and vascular responses, contributing to the understanding of cardiovascular diseases.
  • Pharmacological Studies: It serves as a valuable tool in pharmacology for evaluating the role of adrenergic receptors, helping scientists develop new medications targeting these pathways.
  • Veterinary Medicine: The compound is also applied in veterinary practices to manage hypertension in animals, showcasing its versatility beyond human medicine.

Citations