Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38167
CAS Number:
110429-35-1
Paroxetine hydrochloride hemihydrate
Purity:
≥ 98% (Assay, HPLC)
Synonym(s):
(3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidinehydrochloride hemihydrate, Paroxetine hydrochloride hemihydrate
Documents
$208.31 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Paroxetine hydrochloride hemihydrate is a selective serotonin reuptake inhibitor (SSRI) widely recognized for its efficacy in treating major depressive disorder, anxiety disorders, and obsessive-compulsive disorder. This compound is characterized by its unique structure, which includes a benzodioxole moiety that enhances its pharmacological properties. Its ability to selectively inhibit the reuptake of serotonin makes it a valuable tool in psychiatric medicine, providing relief to patients by improving mood and reducing anxiety levels.

In addition to its therapeutic applications, paroxetine hydrochloride hemihydrate is also utilized in research settings to explore the mechanisms of serotonin modulation and its effects on various neurological conditions. Its stability and solubility in aqueous solutions make it suitable for formulation in various dosage forms, including tablets and oral solutions. Researchers and pharmaceutical developers benefit from its well-documented safety profile and established efficacy, making it a preferred choice in both clinical and laboratory environments.

Synonyms
(3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidinehydrochloride hemihydrate, Paroxetine hydrochloride hemihydrate
CAS Number
110429-35-1
Purity
≥ 98% (Assay, HPLC)
Molecular Formula
C19H20FNO3·HCl·0.5H2O
Molecular Weight
374.84
MDL Number
MFCD03658863
PubChem ID
75110681
Melting Point
142 °C (dec.)
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]D20 = -88 to -92 ° (C=1 in MeOH) (calcd.on anh.substance)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidinehydrochloride hemihydrate, Paroxetine hydrochloride hemihydrate
CAS Number
110429-35-1
Purity
≥ 98% (Assay, HPLC)
Molecular Formula
C19H20FNO3·HCl·0.5H2O
Molecular Weight
374.84
MDL Number
MFCD03658863
PubChem ID
75110681
Melting Point
142 °C (dec.)
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]D20 = -88 to -92 ° (C=1 in MeOH) (calcd.on anh.substance)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Paroxetine hydrochloride hemihydrate is widely utilized in research focused on:

  • Antidepressant Development: Commonly used in the pharmaceutical industry for developing medications targeting depression and anxiety disorders, offering effective serotonin reuptake inhibition.
  • Clinical Trials: A key compound in clinical studies to evaluate treatment efficacy and safety for various mental health conditions, providing valuable data for researchers.
  • Formulation Studies: Employed in the formulation of oral medications, allowing for improved bioavailability and patient compliance due to its favorable pharmacokinetic properties.
  • Behavioral Research: Utilized in animal studies to investigate the effects of serotonin modulation on behavior, aiding in the understanding of mood disorders.
  • Drug Interaction Studies: Important for assessing potential interactions with other medications, helping healthcare professionals make informed prescribing decisions.

Citations