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Probenecid
Probenecid is widely utilized in research focused on
- Gout Treatment: Probenecid is primarily used to manage gout by increasing uric acid excretion in the kidneys, helping to lower uric acid levels in the blood and prevent painful flare-ups.
- Enhancing Antibiotic Efficacy: In clinical settings, it is employed to prolong the action of certain antibiotics, such as penicillin, by inhibiting their renal excretion, thus allowing for lower doses and reduced side effects.
- Pharmacokinetic Studies: Researchers use probenecid in pharmacokinetic studies to understand drug interactions and metabolism, particularly in assessing how drugs are absorbed, distributed, and eliminated by the body.
- Research on Renal Function: It serves as a valuable tool in nephrology research, helping scientists investigate renal function and the mechanisms of renal transport processes.
- Potential Cancer Research: Emerging studies suggest probenecid may have applications in cancer therapy, as it can influence the transport of certain anticancer drugs, potentially enhancing their effectiveness.
General Information
Properties
Safety and Regulations
Applications
Probenecid is widely utilized in research focused on
- Gout Treatment: Probenecid is primarily used to manage gout by increasing uric acid excretion in the kidneys, helping to lower uric acid levels in the blood and prevent painful flare-ups.
- Enhancing Antibiotic Efficacy: In clinical settings, it is employed to prolong the action of certain antibiotics, such as penicillin, by inhibiting their renal excretion, thus allowing for lower doses and reduced side effects.
- Pharmacokinetic Studies: Researchers use probenecid in pharmacokinetic studies to understand drug interactions and metabolism, particularly in assessing how drugs are absorbed, distributed, and eliminated by the body.
- Research on Renal Function: It serves as a valuable tool in nephrology research, helping scientists investigate renal function and the mechanisms of renal transport processes.
- Potential Cancer Research: Emerging studies suggest probenecid may have applications in cancer therapy, as it can influence the transport of certain anticancer drugs, potentially enhancing their effectiveness.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.