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Catalog Number:
38132
CAS Number:
61825-94-3
Oxaliplatin
Synonym(s):
(trans-1,2-Cyclohexanediamine)oxalatoplatinum(II), [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioata(2--)-O,O']platinum
Documents
$181.10 /100MG
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Product Information

Oxaliplatin is a platinum-based chemotherapeutic agent widely recognized for its efficacy in treating various forms of cancer, particularly colorectal cancer. This compound operates by interfering with DNA replication, thereby inhibiting the growth of cancer cells. Its unique mechanism of action, which involves the formation of DNA cross-links, makes it a valuable option in combination therapies, enhancing the effectiveness of other anticancer drugs. Oxaliplatin is particularly advantageous due to its reduced risk of neurotoxicity compared to other platinum compounds, making it a preferred choice for oncologists when developing treatment regimens.

In clinical settings, Oxaliplatin is often used in conjunction with 5-fluorouracil and leucovorin in the FOLFOX regimen, demonstrating significant improvements in patient outcomes. Its versatility extends beyond colorectal cancer, as it is also being explored for use in other malignancies, including gastric and pancreatic cancers. Researchers and healthcare professionals appreciate Oxaliplatin for its ability to overcome resistance mechanisms that often limit the effectiveness of traditional chemotherapy, positioning it as a critical tool in the ongoing fight against cancer.

Synonyms
(trans-1,2-Cyclohexanediamine)oxalatoplatinum(II), [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioata(2--)-O,O']platinum
CAS Number
61825-94-3
Molecular Formula
C8H14N2O4Pt
Molecular Weight
397.29
MDL Number
MFCD00866327
PubChem ID
77994
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(trans-1,2-Cyclohexanediamine)oxalatoplatinum(II), [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioata(2--)-O,O']platinum
CAS Number
61825-94-3
Molecular Formula
C8H14N2O4Pt
Molecular Weight
397.29
MDL Number
MFCD00866327
PubChem ID
77994
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Oxaliplatin is widely utilized in research focused on

  • Cancer Treatment: Primarily used in chemotherapy for colorectal cancer, it helps to inhibit cancer cell growth effectively.
  • Combination Therapies: Often combined with other chemotherapeutic agents to enhance efficacy and overcome drug resistance in patients.
  • Research on Drug Resistance: Valuable in studies aimed at understanding and combating resistance mechanisms in cancer cells, providing insights for developing new treatments.
  • Pharmaceutical Development: Used in the formulation of new cancer drugs, helping researchers design more effective therapies with fewer side effects.
  • Clinical Trials: Frequently involved in clinical research to evaluate its effectiveness and safety, contributing to advancements in oncology.

Citations