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Catalog Number:
38108
CAS Number:
894-71-3
Nortriptyline hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanaminehydrochloride, 10,11-Dihydro-5-(N-methyl-3-aminopropylidene)-5H-dibenzo[a,d]cycloheptenehydrochloride
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Product Information

Nortriptyline hydrochloride is a tricyclic antidepressant renowned for its efficacy in treating major depressive disorders and certain types of chronic pain. This compound functions primarily by inhibiting the reuptake of norepinephrine and serotonin, which enhances mood and alleviates pain. Its unique structure allows it to penetrate the central nervous system effectively, making it a preferred choice for healthcare professionals when addressing treatment-resistant depression or neuropathic pain.

In addition to its antidepressant properties, Nortriptyline hydrochloride has been utilized in various clinical settings, including the management of migraines and anxiety disorders. Its versatility in applications makes it a valuable asset in both pharmaceutical research and therapeutic practices. Researchers appreciate its well-documented safety profile and the potential for combination therapies, which can enhance patient outcomes. With its established role in mental health and pain management, Nortriptyline hydrochloride continues to be a significant compound in the pharmaceutical landscape.

Synonyms
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanaminehydrochloride, 10,11-Dihydro-5-(N-methyl-3-aminopropylidene)-5H-dibenzo[a,d]cycloheptenehydrochloride
CAS Number
894-71-3
Purity
≥ 98% (HPLC)
Molecular Formula
C19H21N·HCl
Molecular Weight
299.84
MDL Number
MFCD00058024
PubChem ID
13468
Melting Point
216 - 220 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanaminehydrochloride, 10,11-Dihydro-5-(N-methyl-3-aminopropylidene)-5H-dibenzo[a,d]cycloheptenehydrochloride
CAS Number
894-71-3
Purity
≥ 98% (HPLC)
Molecular Formula
C19H21N·HCl
Molecular Weight
299.84
MDL Number
MFCD00058024
PubChem ID
13468
Melting Point
216 - 220 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nortriptyline hydrochloride is widely utilized in research focused on:

  • Depression Treatment: Commonly prescribed as an antidepressant, it helps alleviate symptoms of major depressive disorder, providing relief for patients who may not respond to other treatments.
  • Pain Management: Effective in treating chronic pain conditions, such as neuropathic pain, it offers an alternative for patients seeking relief without relying solely on opioids.
  • Sleep Disorders: Often used off-label to treat insomnia, it can improve sleep quality for individuals struggling with sleep disturbances, enhancing overall well-being.
  • Research in Neuropharmacology: Serves as a valuable tool in studying the mechanisms of neurotransmitter regulation, aiding researchers in understanding mood disorders and their treatments.
  • Combination Therapies: Frequently included in multi-drug regimens for complex cases, it can enhance the efficacy of other medications, providing a more comprehensive approach to treatment.

Citations