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Catalog Number:
38100
CAS Number:
75530-68-6
Nilvadipine
Purity:
≥ 98% (HPLC)
Synonym(s):
2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid 5-isopropyl 3-Methyl ester, 5-isopropyl 3-methyl2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
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$165.65 /1G
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Product Information

Nilvadipine is a potent dihydropyridine calcium channel blocker primarily used in the treatment of hypertension and angina. This compound is recognized for its ability to selectively inhibit calcium influx into vascular smooth muscle and cardiac cells, leading to vasodilation and reduced blood pressure. Its unique structure, featuring a cyano group and nitrophenyl moiety, enhances its pharmacological profile, making it effective in managing cardiovascular conditions. Researchers and healthcare professionals appreciate Nilvadipine for its favorable side effect profile compared to other calcium channel blockers, which can lead to improved patient compliance.

In addition to its therapeutic applications, Nilvadipine has garnered interest in research settings for its potential neuroprotective effects, particularly in the context of neurodegenerative diseases. Studies suggest that it may help in protecting neuronal cells from calcium overload, thus opening avenues for further exploration in neurological research. Its versatility in both clinical and research applications makes Nilvadipine a valuable compound for professionals in the pharmaceutical and medical fields.

Synonyms
2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid 5-isopropyl 3-Methyl ester, 5-isopropyl 3-methyl2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
CAS Number
75530-68-6
Purity
≥ 98% (HPLC)
Molecular Formula
C19H19N3O6
Molecular Weight
385.38
MDL Number
MFCD00867065
PubChem ID
4494
Melting Point
149 - 153 °C
Appearance
Light yellow to amber to dark green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid 5-isopropyl 3-Methyl ester, 5-isopropyl 3-methyl2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
CAS Number
75530-68-6
Purity
≥ 98% (HPLC)
Molecular Formula
C19H19N3O6
Molecular Weight
385.38
MDL Number
MFCD00867065
PubChem ID
4494
Melting Point
149 - 153 °C
Appearance
Light yellow to amber to dark green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nilvadipine is widely utilized in research focused on:

  • Hypertension Treatment: Commonly prescribed for managing high blood pressure, it helps improve blood flow and reduce cardiovascular risks.
  • Neuroprotective Research: Investigated for its potential benefits in neurodegenerative diseases, such as Alzheimer's, by improving cerebral blood flow.
  • Cardiovascular Health Studies: Used in clinical trials to assess its effectiveness in preventing heart-related diseases, offering insights into heart health management.
  • Pharmaceutical Development: Employed in the formulation of new medications, providing a basis for developing innovative treatments for various cardiovascular conditions.
  • Drug Interaction Studies: Useful in research examining how different medications interact, helping to optimize treatment regimens for patients with multiple health issues.

Citations