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Catalog Number:
37994
CAS Number:
124750-99-8
Losartan potassium
Purity:
≥ 98% (HPLC)
Synonym(s):
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]imidazole-5-methanolpotassium salt
Documents
$152.33 /5G
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Product Information

Losartan potassium is a highly effective angiotensin II receptor antagonist primarily used in the treatment of hypertension and to protect the kidneys in patients with type 2 diabetes. This compound works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thereby lowering blood pressure and improving blood flow. Its unique structure allows for enhanced selectivity and potency, making it a preferred choice in cardiovascular therapies.

In addition to its primary use in hypertension management, Losartan potassium has shown promise in various research applications, including studies focused on heart failure and chronic kidney disease. Its ability to reduce proteinuria and improve renal function highlights its significance in nephrology. Researchers and healthcare professionals appreciate its favorable safety profile and the convenience of once-daily dosing, which enhances patient compliance. Overall, Losartan potassium stands out for its dual benefits in both clinical and research settings, making it a valuable compound in the pharmaceutical landscape.

Synonyms
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]imidazole-5-methanolpotassium salt
CAS Number
124750-99-8
Purity
≥ 98% (HPLC)
Molecular Formula
C22H22ClKN6O
Molecular Weight
461.01
MDL Number
MFCD02092704
PubChem ID
11476710
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]imidazole-5-methanolpotassium salt
CAS Number
124750-99-8
Purity
≥ 98% (HPLC)
Molecular Formula
C22H22ClKN6O
Molecular Weight
461.01
MDL Number
MFCD02092704
PubChem ID
11476710
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Losartan potassium is widely utilized in research focused on:

  • Hypertension Treatment: Primarily used as an antihypertensive medication, it helps lower blood pressure, making it essential for patients with hypertension.
  • Heart Failure Management: It is beneficial in treating heart failure, providing relief and improving the quality of life for patients with this condition.
  • Diabetic Nephropathy: Losartan potassium is effective in protecting kidney function in patients with diabetes, reducing the risk of kidney damage.
  • Research in Cardiovascular Health: It is frequently studied in clinical trials aimed at understanding its effects on cardiovascular health and its potential benefits in preventing heart-related diseases.
  • Combination Therapies: Often used in conjunction with other antihypertensive agents, it enhances treatment efficacy, allowing for lower doses of each medication and minimizing side effects.

Citations