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Catalog Number:
22181
CAS Number:
67-20-9
Nitrofurantoin
Grade:
Meets USP specification
Purity:
98 - 102% (Assay on anhydrous basis)
Synonym(s):
1-[(5-Nitrofurfurylidene)amino]hydantoin, Furadoxyl
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Product Information

Nitrofurantoin is a potent antimicrobial agent primarily used in the treatment of urinary tract infections (UTIs). This compound operates by inhibiting bacterial cell wall synthesis and disrupting various metabolic processes, making it effective against a wide range of gram-positive and gram-negative bacteria. Its unique mechanism of action allows it to remain effective even in the presence of certain resistant strains, providing a reliable option for healthcare professionals. Nitrofurantoin is particularly valued in clinical settings for its targeted action and minimal side effects, making it a preferred choice for treating uncomplicated UTIs in both adults and children.

In addition to its primary use in treating infections, Nitrofurantoin has potential applications in research settings, particularly in studies focused on antibiotic resistance and the development of new antimicrobial therapies. Its favorable pharmacokinetic profile, including rapid absorption and excretion, enhances its utility in clinical practice. Researchers and industry professionals appreciate Nitrofurantoin for its effectiveness, safety profile, and the growing need for reliable treatments in an era of increasing antibiotic resistance.

Synonyms
1-[(5-Nitrofurfurylidene)amino]hydantoin, Furadoxyl
CAS Number
67-20-9
Purity
98 - 102% (Assay on anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C8H6N4O5
Molecular Weight
238.16
MDL Number
MFCD00003224
PubChem ID
4509
Melting Point
267 - 269 °C (Lit.)
Appearance
Yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
1-[(5-Nitrofurfurylidene)amino]hydantoin, Furadoxyl
CAS Number
67-20-9
Purity
98 - 102% (Assay on anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C8H6N4O5
Molecular Weight
238.16
MDL Number
MFCD00003224
PubChem ID
4509
Melting Point
267 - 269 °C (Lit.)
Appearance
Yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nitrofurantoin is widely utilized in research focused on:

  • Antibiotic Treatment: Primarily used to treat urinary tract infections (UTIs), offering a targeted approach against specific bacteria, making it a preferred choice in clinical settings.
  • Pharmaceutical Development: Serves as a model compound in the development of new antibiotics, helping researchers understand mechanisms of action and resistance.
  • Veterinary Medicine: Applied in treating infections in animals, particularly in livestock, ensuring animal health and productivity.
  • Research on Drug Resistance: Utilized in studies examining bacterial resistance patterns, aiding in the development of strategies to combat antibiotic resistance.
  • Formulation Science: Involved in the formulation of various dosage forms, including tablets and suspensions, allowing for improved patient compliance and effectiveness.

Citations