Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
22047
CAS Number:
124-87-8
Picrotoxin
Purity:
≥ 98% (HPLC)
Synonym(s):
Cocculin
Hazmat
Documents
$43.87 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Picrotoxin is a potent chemical compound recognized for its unique properties and applications in various fields, particularly in neuroscience and pharmacology. This bicyclic compound is primarily known for its role as a non-competitive antagonist of the GABA receptor, making it a valuable tool in research focused on the central nervous system. Researchers utilize Picrotoxin to study the effects of GABAergic inhibition, which is crucial for understanding various neurological disorders, including epilepsy and anxiety. Its ability to induce convulsions in animal models also aids in the exploration of anticonvulsant drugs and their mechanisms of action.

In addition to its research applications, Picrotoxin has been historically used as a stimulant and is being investigated for potential therapeutic uses in treating certain types of poisoning and as an antidote in specific cases. Its unique structure allows for targeted modifications, which can lead to the development of novel compounds with enhanced efficacy. With its diverse applications and ongoing research, Picrotoxin remains a significant compound for professionals in the pharmaceutical and biochemical industries.

Synonyms
Cocculin
CAS Number
124-87-8
Purity
≥ 98% (HPLC)
Molecular Formula
C15H18O7·C15H16O6
Molecular Weight
602.59
MDL Number
MFCD00074824
PubChem ID
518601
Melting Point
199 - 202 ?C
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Cocculin
CAS Number
124-87-8
Purity
≥ 98% (HPLC)
Molecular Formula
C15H18O7·C15H16O6
Molecular Weight
602.59
MDL Number
MFCD00074824
PubChem ID
518601
Melting Point
199 - 202 ?C
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Picrotoxin is widely utilized in research focused on:

  • Neuroscience Research: It serves as a potent antagonist of the GABA receptor, making it essential for studying neurotransmission and the effects of GABAergic drugs.
  • Pharmacology: Used in drug development, it helps researchers understand the mechanisms of action for various sedatives and anxiolytics, aiding in the design of safer medications.
  • Toxicology Studies: Picrotoxin is valuable in assessing the toxicity of compounds, allowing researchers to evaluate the safety profiles of new drugs and chemicals.
  • Behavioral Studies: In animal models, it is used to induce seizures, helping scientists explore epilepsy and seizure disorders, which can lead to better treatment options.
  • Antidote Research: Investigating its potential as an antidote for certain types of poisoning, particularly those involving GABAergic agents, contributes to emergency medicine advancements.

Citations