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Catalog Number:
32457
CAS Number:
5949-11-1
Cinchonine monohydrochloride hydrate
Purity:
≥ 99% (HPLC,T)
Synonym(s):
Cinchonan-9(S-ol monohydrochloride
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Product Information

Cinchonine monohydrochloride hydrate is a versatile compound renowned for its applications in the pharmaceutical and chemical industries. This alkaloid derivative, primarily sourced from the bark of the cinchona tree, exhibits notable antimalarial properties, making it a valuable ingredient in the development of treatments for malaria and other parasitic infections. Its unique structure allows for effective interaction with biological systems, enhancing its efficacy in medicinal formulations.

In addition to its therapeutic uses, cinchonine monohydrochloride hydrate serves as a chiral auxiliary in asymmetric synthesis, facilitating the production of enantiomerically pure compounds. This characteristic is particularly beneficial for researchers and industry professionals engaged in drug development and synthesis, as it streamlines processes and improves yield. With its dual role in both medicinal chemistry and synthetic applications, cinchonine monohydrochloride hydrate stands out as a compound of significant relevance and utility in contemporary research and industry settings.

Synonyms
Cinchonan-9(S-ol monohydrochloride
CAS Number
5949-11-1
Purity
≥ 99% (HPLC,T)
Molecular Formula
C19H22N2O·HCl·H2O
Molecular Weight
330.86
MDL Number
MFCD00191936
PubChem ID
3035282
Melting Point
208-218 °C
Appearance
White powder
Optical Rotation
[a]20/D= +101° (C = 1 in CHCl3)
Conditions
Store at RT
General Information
Synonyms
Cinchonan-9(S-ol monohydrochloride
CAS Number
5949-11-1
Purity
≥ 99% (HPLC,T)
Molecular Formula
C19H22N2O·HCl·H2O
Molecular Weight
330.86
MDL Number
MFCD00191936
PubChem ID
3035282
Melting Point
208-218 °C
Appearance
White powder
Optical Rotation
[a]20/D= +101° (C = 1 in CHCl3)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cinchonine monohydrochloride hydrate is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is integral in the synthesis of various medications, particularly in the treatment of malaria and other parasitic infections, enhancing therapeutic efficacy.
  • Analytical Chemistry: It serves as a chiral resolving agent in chromatography, helping researchers separate enantiomers effectively, which is crucial for drug formulation and quality control.
  • Natural Product Synthesis: Used as a building block in the synthesis of complex natural products, it aids chemists in developing new compounds with potential medicinal properties.
  • Biochemical Research: Its role as a ligand in biochemical assays allows for the study of various biological processes, providing insights into enzyme activity and receptor interactions.
  • Organic Synthesis: Cinchonine monohydrochloride hydrate is employed in asymmetric synthesis, offering advantages in producing compounds with high optical purity, which is essential in pharmaceuticals.

Citations