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Catalog Number:
39691
CAS Number:
30364-60-4
Disuccinimidyl succinate
Purity:
≥ 98% (NMR)
Synonym(s):
Succinic acid disuccinimidyl ester
Documents
$64.90 /100MG
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Product Information

Disuccinimidyl succinate is a versatile crosslinking agent widely utilized in bioconjugation and protein modification applications. This compound, known for its ability to form stable amide bonds, is particularly valuable in the development of antibody-drug conjugates (ADCs) and other therapeutic biomolecules. Researchers appreciate its efficiency in enhancing the stability and efficacy of biologics, making it an essential tool in drug development and protein engineering.

With its unique structure, Disuccinimidyl succinate offers advantages over traditional crosslinkers, such as improved solubility and reduced steric hindrance, which can lead to more effective conjugation reactions. Its applications extend to the creation of novel biomaterials and diagnostic tools, where precise control over molecular interactions is crucial. This compound is ideal for researchers looking to streamline their processes and achieve superior results in their projects.

Synonyms
Succinic acid disuccinimidyl ester
CAS Number
30364-60-4
Purity
≥ 98% (NMR)
Molecular Formula
C12H12N2O8
Molecular Weight
312.23
MDL Number
MFCD00228233
PubChem ID
161662
Melting Point
306 °C (Lit.)
Appearance
White to off-white solid
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Succinic acid disuccinimidyl ester
CAS Number
30364-60-4
Purity
≥ 98% (NMR)
Molecular Formula
C12H12N2O8
Molecular Weight
312.23
MDL Number
MFCD00228233
PubChem ID
161662
Melting Point
306 °C (Lit.)
Appearance
White to off-white solid
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Disuccinimidyl succinate is widely utilized in research focused on:

  • Protein Cross-Linking: This compound serves as a versatile cross-linker in bioconjugation, allowing researchers to create stable protein complexes for studying protein interactions and functions.
  • Vaccine Development: It is employed in the formulation of vaccines, enhancing the stability and efficacy of antigens by facilitating their conjugation to carrier proteins.
  • Drug Delivery Systems: The compound is used to modify nanoparticles, improving the targeted delivery of therapeutic agents in cancer treatment and other diseases.
  • Diagnostic Assays: In the field of diagnostics, it aids in the development of assays by linking biomolecules, which enhances the sensitivity and specificity of detection methods.
  • Biomaterials: Disuccinimidyl succinate is utilized in creating biocompatible materials for tissue engineering, promoting cell adhesion and growth in regenerative medicine applications.

Citations