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Catalog Number:
37489
CAS Number:
1309649-57-7
Biotin-PEG4-azide
Purity:
≥ 96% (HPLC)
Synonym(s):
N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide
Documents
$590.89 /100MG
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Product Information

Biotin-PEG4-azide is a versatile compound that combines the essential vitamin biotin with a polyethylene glycol (PEG) linker and an azide functional group, making it an invaluable tool in bioconjugation and drug delivery applications. This compound is particularly beneficial for researchers in the fields of biochemistry and molecular biology, as it facilitates the attachment of biomolecules to surfaces or other compounds through click chemistry. The PEG component enhances solubility and biocompatibility, while the azide group allows for efficient coupling with alkyne-containing partners, streamlining the synthesis of complex biomolecular constructs.

In practical applications, Biotin-PEG4-azide is widely used in the development of targeted therapeutics, diagnostics, and imaging agents. For instance, it can be employed to label proteins or antibodies for use in various assays, including ELISA and Western blotting, thereby improving detection sensitivity. Additionally, its unique properties make it suitable for creating biotinylated nanoparticles, which can be utilized in targeted drug delivery systems. Researchers can leverage the advantages of Biotin-PEG4-azide to enhance their experimental outcomes and develop innovative solutions in the life sciences.

Synonyms
N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide
CAS Number
1309649-57-7
Purity
≥ 96% (HPLC)
Molecular Formula
C20H36N6O6S
Molecular Weight
488.6
MDL Number
MFCD29495433
PubChem ID
75412430
Melting Point
102 - 106 °C
Appearance
White to orange to green powder to crystal
Conditions
Store at ≤ -10 °C
General Information
Synonyms
N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide
CAS Number
1309649-57-7
Purity
≥ 96% (HPLC)
Molecular Formula
C20H36N6O6S
Molecular Weight
488.6
MDL Number
MFCD29495433
PubChem ID
75412430
Melting Point
102 - 106 °C
Appearance
White to orange to green powder to crystal
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Biotin-PEG4-azide is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: Its unique properties allow for the creation of advanced drug delivery systems that improve the efficacy and specificity of therapeutic agents, particularly in cancer treatment.
  • Fluorescent Labeling: Researchers use Biotin-PEG4-azide for fluorescent labeling of biomolecules, enabling visualization and tracking in live cell imaging studies, which is crucial for understanding cellular processes.
  • Protein Purification: This compound aids in the purification of proteins through affinity chromatography, providing a reliable method for isolating proteins of interest from complex mixtures.
  • Diagnostics Development: Its application in the development of diagnostic assays enhances sensitivity and specificity, making it valuable in creating reliable tests for various diseases.

Citations