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Catalog Number:
37487
CAS Number:
26929-65-7
2'-Azido-2'-deoxyuridine
Purity:
≥ 98% (HPLC)
Synonym(s):
N3-dU
Documents
$221.63 /25MG
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Product Information

2'-Azido-2'-deoxyuridine is a versatile nucleoside analog that has garnered significant attention in the fields of molecular biology and medicinal chemistry. This compound is primarily utilized in the synthesis of modified nucleic acids, making it an invaluable tool for researchers exploring gene therapy, antiviral drug development, and the study of nucleic acid interactions. Its unique azido group enhances its reactivity, allowing for the incorporation into DNA strands, which can be pivotal in the design of novel therapeutic agents targeting viral infections and cancer.

Moreover, 2'-Azido-2'-deoxyuridine has shown potential in the development of antiviral therapies, particularly against HIV and other retroviruses, due to its ability to inhibit viral replication. Its structural similarity to natural nucleosides allows for effective incorporation into viral genomes, disrupting their function. Researchers appreciate its stability and compatibility with various biochemical assays, making it a preferred choice for studies involving nucleic acid manipulation and modification. With its promising applications in both research and therapeutic contexts, 2'-Azido-2'-deoxyuridine stands out as a crucial compound for advancing scientific understanding and developing innovative treatments.

Synonyms
N3-dU
CAS Number
26929-65-7
Purity
≥ 98% (HPLC)
Molecular Formula
C9H11N5O5
Molecular Weight
269.22
MDL Number
MFCD00043045
PubChem ID
386489
Melting Point
151 °C (dec.) (Lit.)
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N3-dU
CAS Number
26929-65-7
Purity
≥ 98% (HPLC)
Molecular Formula
C9H11N5O5
Molecular Weight
269.22
MDL Number
MFCD00043045
PubChem ID
386489
Melting Point
151 °C (dec.) (Lit.)
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2'-Azido-2'-deoxyuridine is widely utilized in research focused on:

  • Antiviral Research: This compound is used in the development of antiviral drugs, particularly against HIV. Its azido group enhances its ability to inhibit viral replication, making it a valuable tool in pharmaceutical research.
  • Gene Therapy: It serves as a nucleoside analog in gene therapy applications. Researchers use it to modify nucleic acids, which can help in delivering therapeutic genes more effectively to target cells.
  • Bioconjugation: The azido group allows for click chemistry applications, facilitating the attachment of biomolecules in drug development and diagnostics. This is particularly useful in creating targeted therapies.
  • Cellular Imaging: It can be incorporated into DNA for imaging studies, helping researchers visualize cellular processes and track the behavior of specific genes or proteins in living organisms.
  • Research on Nucleic Acid Modifications: The compound is instrumental in studying the effects of nucleoside modifications on DNA and RNA stability, which is crucial for understanding genetic diseases and developing new treatments.

Citations