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Catalog Number:
35132
F-ara-EdU
Purity:
≥ 95% (HPLC)
Documents
$177.30 /5MG
Pack Size Availability Price
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Product Information

F-ara-EdU is a novel nucleoside analog that has garnered significant attention in the fields of molecular biology and cancer research. This compound is recognized for its unique ability to incorporate into DNA during replication, allowing researchers to track cellular proliferation and study DNA synthesis with high precision. Its structural similarity to thymidine makes it an invaluable tool for studying cell division and the effects of various treatments on rapidly dividing cells. F-ara-EdU is particularly useful in assays such as click chemistry, enabling the visualization of newly synthesized DNA in live cells, which is crucial for understanding cellular dynamics in cancer and other diseases.

The compound's advantages over traditional nucleoside analogs include its enhanced stability and lower toxicity, making it a preferred choice for in vivo studies. Researchers have successfully utilized F-ara-EdU in various applications, including drug efficacy testing, cell cycle analysis, and the investigation of DNA repair mechanisms. Its ability to provide clear and quantifiable results positions F-ara-EdU as a critical reagent in advancing our understanding of cellular processes and therapeutic interventions.

Purity
≥ 95% (HPLC)
Molecular Formula
C11H11NF2O5
Molecular Weight
270.22
Appearance
Off white to grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Purity
≥ 95% (HPLC)
Molecular Formula
C11H11NF2O5
Molecular Weight
270.22
Appearance
Off white to grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

F-ara-EdU is widely utilized in research focused on:

  • Cell Proliferation Studies: This compound is an effective tool for tracking cell division in various biological systems, allowing researchers to visualize and quantify proliferating cells in real-time.
  • DNA Synthesis Monitoring: F-ara-EdU can be incorporated into newly synthesized DNA, making it invaluable for studies aimed at understanding DNA replication and repair mechanisms.
  • Cancer Research: Its application in cancer studies helps in assessing the effectiveness of anti-cancer therapies by measuring the impact on tumor cell proliferation.
  • Neuroscience: Researchers use F-ara-EdU to label dividing neural progenitor cells, aiding in the investigation of neurogenesis and brain development.
  • Drug Development: In pharmaceutical research, it assists in evaluating the effects of new compounds on cell growth, providing insights into their potential therapeutic benefits.

Citations