Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
35111
Azido-PEG3-maleimide
Documents
$108.20 /5MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Azido-PEG3-maleimide is a versatile compound widely utilized in bioconjugation and drug delivery applications. This chemical features a unique azide functional group that allows for click chemistry reactions, enabling efficient and selective conjugation to biomolecules such as proteins, peptides, and nucleic acids. The PEG (polyethylene glycol) moiety enhances solubility and biocompatibility, making it an ideal choice for researchers looking to develop targeted therapies or diagnostic tools. Its maleimide group provides a reactive site for thiol-containing molecules, facilitating the formation of stable thioether bonds.

In practical applications, Azido-PEG3-maleimide is employed in the development of antibody-drug conjugates (ADCs), where it plays a crucial role in linking cytotoxic drugs to antibodies for targeted cancer therapy. Additionally, it is used in the creation of fluorescent probes for imaging studies, allowing for real-time tracking of biological processes. The compound's ability to streamline conjugation processes while maintaining the integrity of biomolecules makes it a valuable asset in both academic and industrial research settings.

Molecular Formula
C15H23N5O6
Molecular Weight
369.37
Appearance
Colorless to slightly yellow oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Molecular Formula
C15H23N5O6
Molecular Weight
369.37
Appearance
Colorless to slightly yellow oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Azido-PEG3-maleimide is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins and antibodies, to other molecules. Its azide group allows for click chemistry reactions, making it a powerful tool in developing targeted therapies and diagnostics.
  • Drug Delivery Systems: The PEG component enhances solubility and biocompatibility, making it ideal for creating drug delivery systems that improve the stability and efficacy of therapeutic agents.
  • Fluorescent Labeling: Researchers use this compound to attach fluorescent tags to biomolecules, facilitating the study of cellular processes and interactions in real-time imaging applications.
  • Surface Modification: It is employed in modifying surfaces of materials, such as nanoparticles and implants, to improve their interaction with biological systems, enhancing their performance in medical applications.
  • Diagnostics Development: The compound plays a crucial role in the development of diagnostic tools, such as biosensors, where precise labeling and detection of biomolecules are necessary for accurate results.

Citations