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Catalog Number:
35085
CAS Number:
1609659-01-9
TCO-PEG3-maleimide
Purity:
≥ 99% (HPLC)
Synonym(s):
trans-Cyclooctene-PEG3-maleimide
Documents
$145.00 /5MG
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Product Information

TCO-PEG3-maleimide is a versatile compound that serves as a valuable tool in bioconjugation and drug delivery applications. This maleimide derivative is particularly useful for the selective labeling of biomolecules, enabling researchers to create stable conjugates with proteins, peptides, and other macromolecules. Its unique structure allows for efficient thiol-reactivity, making it an ideal choice for applications in targeted therapies and diagnostic imaging.

The incorporation of a PEG (polyethylene glycol) moiety enhances the solubility and biocompatibility of TCO-PEG3-maleimide, which is crucial for in vivo applications. This compound is widely utilized in the development of antibody-drug conjugates (ADCs) and other therapeutic modalities, providing researchers with a powerful tool for improving drug efficacy and reducing off-target effects. With its ability to facilitate precise conjugation, TCO-PEG3-maleimide stands out as a preferred choice for professionals seeking reliable solutions in the fields of biochemistry and pharmaceutical development.

Synonyms
trans-Cyclooctene-PEG3-maleimide
CAS Number
1609659-01-9
Purity
≥ 99% (HPLC)
Molecular Formula
C26H41N3O8
Molecular Weight
523.62
MDL Number
MFCD28053553
PubChem ID
146156066
Appearance
Colorless to slightly yellow oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
trans-Cyclooctene-PEG3-maleimide
CAS Number
1609659-01-9
Purity
≥ 99% (HPLC)
Molecular Formula
C26H41N3O8
Molecular Weight
523.62
MDL Number
MFCD28053553
PubChem ID
146156066
Appearance
Colorless to slightly yellow oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

TCO-PEG3-maleimide is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies in drug delivery systems.
  • Fluorescent Labeling: It serves as a linker for fluorescent dyes in imaging applications, allowing researchers to visualize cellular processes and track molecular interactions in real-time.
  • Polymer Chemistry: TCO-PEG3-maleimide is used in the synthesis of advanced polymer materials, which can have applications in drug delivery, tissue engineering, and regenerative medicine due to their biocompatibility.
  • Diagnostics: This compound plays a crucial role in the development of diagnostic tools, enabling the creation of biosensors that can detect specific biomolecules, improving disease diagnosis and monitoring.
  • Vaccine Development: Its ability to facilitate the conjugation of antigens to carriers makes it valuable in vaccine formulation, potentially enhancing immune responses and efficacy in immunotherapy.

Citations