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Catalog Number:
35075
CAS Number:
1416711-60-8
DBCO-PEG4-OH
Purity:
≥ 95% (HPLC)
Synonym(s):
Dibenzocyclooctyne-PEG4-acid
Documents
$108.20 /5MG
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Product Information

DBCO-PEG4-OH is a versatile compound that combines the unique properties of dibenzocyclooctyne (DBCO) with a polyethylene glycol (PEG) moiety, making it an essential tool for bioconjugation applications. This compound features a hydroxyl group that enhances its solubility in aqueous environments, facilitating its use in various biological systems. DBCO-PEG4-OH is particularly valuable in click chemistry, where it serves as a reactive handle for labeling biomolecules, such as proteins and nucleic acids, allowing for precise tracking and imaging in cellular studies. Its ability to form stable covalent bonds with azide-functionalized molecules opens up possibilities for creating complex bioconjugates, which are crucial in drug delivery systems and targeted therapies.

Researchers and industry professionals can leverage DBCO-PEG4-OH in the development of advanced therapeutics and diagnostics. Its unique structure not only improves the efficiency of conjugation reactions but also enhances the stability and bioavailability of the resulting products. This compound is ideal for applications in pharmaceutical research, biomaterials development, and molecular imaging, providing significant advantages over traditional coupling agents by offering greater specificity and reduced side reactions.

Synonyms
Dibenzocyclooctyne-PEG4-acid
CAS Number
1416711-60-8
Purity
≥ 95% (HPLC)
Molecular Formula
C29H36N2O6
Molecular Weight
508.61
PubChem ID
97046974
Appearance
White to slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Dibenzocyclooctyne-PEG4-acid
CAS Number
1416711-60-8
Purity
≥ 95% (HPLC)
Molecular Formula
C29H36N2O6
Molecular Weight
508.61
PubChem ID
97046974
Appearance
White to slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO-PEG4-OH is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker for attaching biomolecules such as proteins, antibodies, or nucleic acids, facilitating targeted drug delivery in therapeutic applications.
  • Drug Development: In pharmaceutical research, it aids in the design of novel drug formulations that enhance solubility and bioavailability, improving the efficacy of treatments.
  • Diagnostics: DBCO-PEG4-OH is employed in the development of diagnostic assays, enabling the precise detection of biomarkers in various diseases, including cancer.
  • Material Science: It is used in creating functionalized surfaces and materials, enhancing properties like biocompatibility and stability for applications in medical devices.
  • Nanotechnology: The compound plays a crucial role in the synthesis of nanoparticles for drug delivery systems, allowing for controlled release and targeted therapy.

Citations