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Catalog Number:
35071
Desthiobiotin-PEG4-DBCO
Purity:
≥ 95% (HPLC)
Synonym(s):
Desthiobiotin-PEG4-dibenzocyclooctyne
Documents
$216.40 /5MG
Pack Size Availability Price
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Product Information

Desthiobiotin-PEG4-DBCO is a versatile chemical compound that serves as a powerful tool in bioconjugation and drug delivery applications. This compound features a unique structure that combines desthiobiotin with a polyethylene glycol (PEG) spacer and a dibenzocyclooctyne (DBCO) moiety, enhancing its solubility and stability in biological environments. Researchers and industry professionals utilize Desthiobiotin-PEG4-DBCO for its ability to facilitate the selective labeling of biomolecules, making it invaluable in the development of targeted therapies and diagnostic tools. Its efficient click chemistry properties allow for rapid and reliable conjugation to proteins, antibodies, and other biomolecules, streamlining the process of creating complex bioconjugates.

The practical applications of Desthiobiotin-PEG4-DBCO extend to various fields, including drug development, molecular imaging, and proteomics. For instance, it can be employed in the synthesis of antibody-drug conjugates (ADCs) that enhance the efficacy of cancer treatments while minimizing side effects. Additionally, its use in the preparation of fluorescently labeled biomolecules aids in cellular imaging studies, providing insights into cellular processes. With its unique features and broad applicability, Desthiobiotin-PEG4-DBCO stands out as a critical component for researchers looking to innovate in the life sciences.

Synonyms
Desthiobiotin-PEG4-dibenzocyclooctyne
Purity
≥ 95% (HPLC)
Molecular Formula
C39H51N5O8
Molecular Weight
719.87
Appearance
Colorless to slightly yellow oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Desthiobiotin-PEG4-dibenzocyclooctyne
Purity
≥ 95% (HPLC)
Molecular Formula
C39H51N5O8
Molecular Weight
719.87
Appearance
Colorless to slightly yellow oil
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Desthiobiotin-PEG4-DBCO is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins or antibodies, to various surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: Its unique structure allows for the creation of advanced drug delivery systems that improve the efficacy and specificity of therapeutic agents, particularly in cancer treatment.
  • Fluorescent Labeling: Researchers use it for fluorescent labeling of biomolecules, facilitating visualization in cellular studies and improving the understanding of biological processes.
  • Surface Functionalization: It is employed in modifying surfaces of nanoparticles and other materials, which is crucial in fields like nanotechnology and material science for creating more efficient sensors and catalysts.
  • Diagnostics Development: The compound plays a significant role in developing diagnostic tools, such as biosensors, that can detect diseases at an early stage, offering a significant advantage in healthcare applications.

Citations