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Catalog Number:
35063
CAS Number:
1395786-30-7
DBCO maleimide
Purity:
≥ 95% (HPLC)
Synonym(s):
Dibenzocyclooctyne-maleimide
Documents
$121.30 /5MG
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Product Information

DBCO maleimide is a versatile chemical compound widely utilized in bioconjugation and drug delivery applications. This compound features a unique structure that allows for efficient and selective reactions with thiol-containing molecules, making it an ideal choice for researchers in the fields of biochemistry and molecular biology. Its ability to form stable linkages with biomolecules enables the development of targeted therapies and diagnostic tools, enhancing the efficacy of drug delivery systems.

In addition to its applications in drug development, DBCO maleimide is also employed in the synthesis of complex biomolecular structures, such as antibody-drug conjugates (ADCs) and fluorescent probes. The compound's stability and reactivity under physiological conditions make it a preferred choice for researchers looking to create innovative solutions in therapeutic and diagnostic applications. With its growing relevance in the pharmaceutical and biotechnology industries, DBCO maleimide stands out as a critical component for advancing research and development efforts.

Synonyms
Dibenzocyclooctyne-maleimide
CAS Number
1395786-30-7
Purity
≥ 95% (HPLC)
Molecular Formula
C25H21N3O4
Molecular Weight
427.75
PubChem ID
77078149
Appearance
Slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Dibenzocyclooctyne-maleimide
CAS Number
1395786-30-7
Purity
≥ 95% (HPLC)
Molecular Formula
C25H21N3O4
Molecular Weight
427.75
PubChem ID
77078149
Appearance
Slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO maleimide is widely utilized in research focused on

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: Its unique reactivity allows for the creation of advanced drug delivery systems, improving the efficacy and specificity of therapeutic agents in treating diseases.
  • Fluorescent Labeling: DBCO maleimide is used in fluorescent labeling techniques, enabling researchers to visualize and track biological processes in live cells, which is crucial for understanding cellular functions.
  • Polymer Chemistry: In polymer science, it serves as a crosslinking agent, contributing to the development of new materials with enhanced mechanical properties and stability for various industrial applications.
  • Diagnostics Development: The compound plays a significant role in the development of diagnostic tools, such as biosensors, which can detect specific biomolecules, aiding in early disease diagnosis and monitoring.

Citations