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Catalog Number:
22998
CAS Number:
39028-27-8
Succinimidyl iodoacetate
Purity:
≥ 98% (HPLC)
Synonym(s):
SIA, Iodoacetic acid N-hydroxysuccinimide ester
Documents
$70.00 /100MG
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Product Information

Succinimidyl iodoacetate is a versatile chemical compound widely utilized in bioconjugation and protein labeling applications. This reagent is particularly valued for its ability to selectively modify proteins and peptides, facilitating the attachment of various biomolecules, such as fluorophores or affinity tags. Its unique structure allows for stable covalent bonding, making it an ideal choice for researchers aiming to enhance the functionality of biomolecules in assays, imaging, and therapeutic applications.

In the field of drug development and diagnostics, Succinimidyl iodoacetate plays a crucial role in the creation of targeted delivery systems and the development of novel therapeutic agents. Its efficiency in forming stable conjugates enables researchers to track and study the behavior of biomolecules in complex biological systems. This compound is also advantageous over similar reagents due to its high reactivity and specificity, ensuring minimal off-target effects. Whether in academic research or industrial applications, Succinimidyl iodoacetate stands out as a reliable tool for advancing scientific discovery.

Synonyms
SIA, Iodoacetic acid N-hydroxysuccinimide ester
CAS Number
39028-27-8
Purity
≥ 98% (HPLC)
Molecular Formula
C6H6NO4I
Molecular Weight
283.02
MDL Number
MFCD00058451
PubChem ID
3299230
Melting Point
146 - 148 °C (Lit.)
Appearance
Off-white solid or yellowish to white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
SIA, Iodoacetic acid N-hydroxysuccinimide ester
CAS Number
39028-27-8
Purity
≥ 98% (HPLC)
Molecular Formula
C6H6NO4I
Molecular Weight
283.02
MDL Number
MFCD00058451
PubChem ID
3299230
Melting Point
146 - 148 °C (Lit.)
Appearance
Off-white solid or yellowish to white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Succinimidyl iodoacetate is widely utilized in research focused on

  • Protein Labeling: This compound is commonly used to label proteins in biochemical assays, allowing researchers to track and study protein interactions and functions effectively.
  • Antibody Conjugation: It serves as a valuable tool for conjugating antibodies to various molecules, enhancing their ability to target specific cells or tissues in therapeutic applications.
  • Drug Development: In pharmaceutical research, it aids in the development of targeted drug delivery systems, improving the efficacy of treatments by ensuring drugs reach their intended sites of action.
  • Bioconjugation Techniques: This chemical is essential in bioconjugation techniques, where it facilitates the attachment of biomolecules to surfaces, enhancing the performance of biosensors and diagnostic tools.
  • Research in Cell Biology: It is used in cell biology studies to modify cell surfaces, helping scientists understand cellular processes and interactions in a more detailed manner.

Citations