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Catalog Number:
02309
CAS Number:
74124-79-1
N,N'-Disuccinimidyl carbonate
Purity:
≥ 98% (HPLC)
Synonym(s):
DSC, Di-N-succinimidylcarbonate
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Product Information

N,N'-Disuccinimidyl carbonate is a versatile crosslinking agent widely utilized in bioconjugation and protein modification applications. This compound is particularly valued for its ability to form stable linkages between biomolecules, making it an essential tool in the development of targeted drug delivery systems and antibody-drug conjugates. Its unique structure allows for the efficient coupling of proteins, peptides, and other biomolecules, enhancing their stability and functionality. Researchers in the fields of biochemistry and molecular biology often leverage N,N'-Disuccinimidyl carbonate for creating complex biomolecular architectures, which can lead to advancements in therapeutic development and diagnostics.

The compound's high reactivity and specificity make it a preferred choice over other crosslinkers, as it minimizes unwanted side reactions and maximizes yield. Additionally, its compatibility with various functional groups allows for a wide range of applications, from vaccine development to the creation of biosensors. By incorporating N,N'-Disuccinimidyl carbonate into their workflows, professionals can achieve more efficient and effective results in their research and product development efforts.

Synonyms
DSC, Di-N-succinimidylcarbonate
CAS Number
74124-79-1
Purity
≥ 98% (HPLC)
Molecular Formula
C9H8N2O7
Molecular Weight
256.2
MDL Number
MFCD00009767
PubChem ID
676246
Melting Point
191 - 222 °C
Appearance
White or off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
DSC, Di-N-succinimidylcarbonate
CAS Number
74124-79-1
Purity
≥ 98% (HPLC)
Molecular Formula
C9H8N2O7
Molecular Weight
256.2
MDL Number
MFCD00009767
PubChem ID
676246
Melting Point
191 - 222 °C
Appearance
White or off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N,N'-Disuccinimidyl carbonate is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile crosslinker for attaching biomolecules, such as proteins and antibodies, to surfaces or other molecules, enhancing the development of targeted therapies and diagnostics.
  • Vaccine Development: It plays a crucial role in the formulation of vaccines by facilitating the conjugation of antigens to carrier proteins, improving immune response and stability.
  • Drug Delivery Systems: Researchers use it to create advanced drug delivery systems that allow for controlled release of therapeutics, increasing efficacy while minimizing side effects.
  • Protein Engineering: The compound is employed in the modification of proteins to study their structure and function, aiding in the design of novel enzymes and therapeutic proteins.
  • Diagnostics: It is utilized in the development of diagnostic assays, where it helps in the immobilization of biomolecules on solid supports, enhancing sensitivity and specificity in detection methods.

Citations