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Catalog Number:
23109
CAS Number:
28537-70-4
1,4-Bis-maleimidobutane
Purity:
≥ 99% (NMR)
Synonym(s):
N,N-(Tetramethylene)dimaleimide
Documents
$221.63 /100MG
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Product Information

1,4-Bis-maleimidobutane is a versatile compound widely utilized in the fields of polymer chemistry and bioconjugation. This bifunctional maleimide derivative is particularly valued for its ability to form stable thioether bonds with thiol-containing molecules, making it an essential reagent for crosslinking proteins and peptides. Its unique structure allows for the creation of robust polymer networks, which are crucial in developing advanced materials for biomedical applications, such as drug delivery systems and tissue engineering scaffolds. Researchers appreciate its high reactivity and specificity, which facilitate the design of tailored biomaterials with enhanced mechanical properties and biocompatibility.

In addition to its applications in bioconjugation, 1,4-Bis-maleimidobutane is also employed in the synthesis of functionalized surfaces and coatings, providing a pathway for the development of sensors and diagnostic tools. Its ability to promote controlled polymerization processes further enhances its utility in creating smart materials with responsive characteristics. Overall, this compound stands out for its reliability and effectiveness in various industrial and research applications, making it a valuable asset for professionals seeking innovative solutions.

Synonyms
N,N-(Tetramethylene)dimaleimide
CAS Number
28537-70-4
Purity
≥ 99% (NMR)
Molecular Formula
C12H12N2O4
Molecular Weight
248.24
MDL Number
MFCD01318342
PubChem ID
239576
Melting Point
196-200 °C
Appearance
White to off-white solid
Conditions
Store at 0-8 °C
General Information
Synonyms
N,N-(Tetramethylene)dimaleimide
CAS Number
28537-70-4
Purity
≥ 99% (NMR)
Molecular Formula
C12H12N2O4
Molecular Weight
248.24
MDL Number
MFCD01318342
PubChem ID
239576
Melting Point
196-200 °C
Appearance
White to off-white solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1,4-Bis-maleimidobutane is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking proteins and other biomolecules, enhancing the development of targeted therapies in pharmaceuticals.
  • Polymer Chemistry: It serves as a crosslinking agent in the synthesis of hydrogels and elastomers, improving the mechanical properties of materials used in medical devices.
  • Diagnostics: Utilized in the creation of biosensors, it helps in the detection of specific biomolecules, which is crucial for early disease diagnosis.
  • Vaccine Development: The compound plays a role in the formulation of vaccine adjuvants, boosting immune responses and improving vaccine efficacy.
  • Material Science: It is used in the production of advanced composite materials, offering enhanced durability and performance in various industrial applications.

Citations