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Catalog Number:
23029
CAS Number:
79886-55-8
Succinimidyl 4-(p-maleimidophenyl)butyrate
Purity:
≥ 99% (HPLC)
Synonym(s):
SMPB, 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimideester
Documents
$148.22 /100MG
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Product Information

Succinimidyl 4-(p-maleimidophenyl)butyrate is a versatile crosslinking reagent widely utilized in bioconjugation applications. This compound features a unique maleimide functionality that allows for selective conjugation to thiol groups, making it an ideal choice for the development of antibody-drug conjugates, protein labeling, and the creation of complex biomolecular structures. Its ability to form stable thioether bonds enhances the stability and efficacy of the resulting conjugates, which is crucial in therapeutic and diagnostic applications. Researchers appreciate its ease of use and the efficiency it brings to the conjugation process, enabling the creation of highly specific and potent biomolecules.

In addition to its applications in drug development, Succinimidyl 4-(p-maleimidophenyl)butyrate is also employed in the fabrication of biosensors and in the study of protein interactions. Its unique properties facilitate the exploration of cellular mechanisms and the development of innovative therapeutic strategies. With its reliable performance and broad applicability, this compound stands out as a valuable tool for researchers and industry professionals seeking to advance their work in biochemistry and molecular biology.

Synonyms
SMPB, 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimideester
CAS Number
79886-55-8
Purity
≥ 99% (HPLC)
Molecular Formula
C18H16N2O6
Molecular Weight
356.32
MDL Number
MFCD00054961
PubChem ID
100681
Melting Point
130 - 132 °C
Appearance
Pale yellow powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
SMPB, 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimideester
CAS Number
79886-55-8
Purity
≥ 99% (HPLC)
Molecular Formula
C18H16N2O6
Molecular Weight
356.32
MDL Number
MFCD00054961
PubChem ID
100681
Melting Point
130 - 132 °C
Appearance
Pale yellow powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Succinimidyl 4-(p-maleimidophenyl)butyrate is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to link proteins, peptides, or antibodies to other molecules, enhancing their functionality in various applications, such as drug delivery systems.
  • Diagnostic Applications: It plays a crucial role in the development of diagnostic tools, allowing for the creation of targeted imaging agents that can improve the accuracy of disease detection.
  • Vaccine Development: Researchers use it to create conjugate vaccines, which can stimulate a stronger immune response by linking antigens to carrier proteins.
  • Cellular Studies: This chemical is employed in cell biology to study protein interactions and cellular signaling pathways, providing insights into disease mechanisms.
  • Therapeutic Applications: Its ability to form stable conjugates makes it valuable in developing targeted therapies, particularly in cancer treatment, where precision is critical.

Citations