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Catalog Number:
22999
CAS Number:
42014-51-7
Succinimidyl bromoacetate
Purity:
≥ 97%
Synonym(s):
SBA, Bromoacetic acid N-hydroxysuccinimide ester
Documents
$100.60 /1G
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Product Information

Succinimidyl bromoacetate is a versatile reagent widely utilized in bioconjugation and protein labeling applications. This compound is particularly valued for its ability to selectively modify amino groups in proteins, facilitating the attachment of various biomolecules, such as fluorescent dyes or therapeutic agents. Its unique structure allows for efficient conjugation, making it an essential tool in the development of targeted drug delivery systems and diagnostic assays. Researchers in the fields of biochemistry and molecular biology often leverage succinimidyl bromoacetate to enhance the specificity and efficacy of their experiments, particularly in the creation of antibody-drug conjugates and in the study of protein interactions.

In addition to its applications in research, succinimidyl bromoacetate is also employed in the development of novel biomaterials and in the synthesis of peptide-based therapeutics. Its ability to form stable covalent bonds with proteins ensures that modifications remain intact under physiological conditions, which is crucial for maintaining the functionality of the modified biomolecules. This compound stands out among similar reagents due to its high reactivity and selectivity, making it a preferred choice for professionals seeking reliable and effective solutions in their research and development endeavors.

Synonyms
SBA, Bromoacetic acid N-hydroxysuccinimide ester
CAS Number
42014-51-7
Purity
≥ 97%
Molecular Formula
C6H6NO4Br
Molecular Weight
237.0
MDL Number
MFCD00058571
PubChem ID
3565210
Melting Point
113 - 119 °C (Lit.)
Appearance
White or slightly red powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
SBA, Bromoacetic acid N-hydroxysuccinimide ester
CAS Number
42014-51-7
Purity
≥ 97%
Molecular Formula
C6H6NO4Br
Molecular Weight
237.0
MDL Number
MFCD00058571
PubChem ID
3565210
Melting Point
113 - 119 °C (Lit.)
Appearance
White or slightly red powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Succinimidyl bromoacetate is widely utilized in research focused on:

  • Bioconjugation: This compound is frequently used to attach biomolecules, such as proteins and antibodies, to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutics.
  • Drug Development: In pharmaceutical research, it serves as a linker in the design of targeted drug delivery systems, improving the efficacy and specificity of treatments.
  • Protein Modification: Researchers employ succinimidyl bromoacetate for site-specific labeling of proteins, which is crucial for studying protein interactions and functions in various biological processes.
  • Fluorescent Probes: It is used in the synthesis of fluorescent probes that help visualize cellular processes, making it invaluable in cell biology and imaging studies.
  • Vaccine Development: The compound plays a role in the development of vaccines by facilitating the conjugation of antigens to carrier proteins, enhancing immune responses.

Citations