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Catalog Number:
07310
CAS Number:
166108-71-0
Fmoc-8-amino-3,6-dioxaoctanoic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, Fmoc-AEEA-OH
Documents
$50.00 /250MG
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Product Information

Fmoc-8-amino-3,6-dioxaoctanoic acid is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure, characterized by the presence of ethylene glycol units, enhances solubility and stability, making it an ideal choice for researchers focused on developing complex peptide sequences.

In practical applications, Fmoc-8-amino-3,6-dioxaoctanoic acid is particularly valuable in the fields of medicinal chemistry and biochemistry, where it serves as a building block for the synthesis of bioactive peptides and therapeutic agents. Its ability to facilitate the formation of stable peptide bonds while maintaining the integrity of sensitive functional groups allows for the creation of peptides with enhanced biological activity. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, making it a preferred choice for those aiming to streamline their synthesis processes and improve yields.

Synonyms
{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, Fmoc-AEEA-OH
CAS Number
166108-71-0
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO6
Molecular Weight
385.42
MDL Number
MFCD01321015
PubChem ID
2756092
Melting Point
85 - 102 °C (Lit.)
Appearance
White powder or crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid, Fmoc-AEEA-OH
CAS Number
166108-71-0
Purity
≥ 99% (HPLC)
Molecular Formula
C21H23NO6
Molecular Weight
385.42
MDL Number
MFCD01321015
PubChem ID
2756092
Melting Point
85 - 102 °C (Lit.)
Appearance
White powder or crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-8-amino-3,6-dioxaoctanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure enhances the solubility and stability of drug candidates, making it valuable in pharmaceutical formulations aimed at improving bioavailability.
  • Bioconjugation: The chemical is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in developing targeted therapies and diagnostics.
  • Research in Biochemistry: It plays a significant role in studying protein interactions and functions, helping researchers understand biological processes and develop new therapeutic strategies.
  • Polymer Chemistry: The compound is employed in the synthesis of functionalized polymers, which can be used in drug delivery systems, enhancing the effectiveness of therapeutic agents.

Citations