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Catalog Number:
35064
Sulfo DBCO-PEG4-maleimide
Purity:
≥ 95% (HPLC)
Synonym(s):
Sulfo dibenzocyclooctyne-PEG4-maleimide
Documents
$180.70 /5MG
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Product Information

Sulfo DBCO-PEG4-maleimide is a highly versatile compound widely utilized in bioconjugation and drug delivery applications. This water-soluble maleimide derivative features a sulfonate group, enhancing its solubility and reactivity, making it an ideal choice for labeling biomolecules such as proteins and peptides. Its unique structure allows for efficient conjugation to thiol-containing compounds, facilitating the development of targeted therapies and diagnostic tools. Researchers appreciate its ability to form stable linkages, which is crucial for maintaining the integrity and functionality of the conjugated molecules.

In the field of biomedical research, Sulfo DBCO-PEG4-maleimide is particularly valuable for creating antibody-drug conjugates (ADCs) and other therapeutic agents. Its PEG4 spacer enhances solubility and reduces immunogenicity, improving the pharmacokinetics of the resulting conjugates. This compound is also employed in the development of fluorescent probes and imaging agents, enabling precise tracking of biological processes. With its robust performance and adaptability, Sulfo DBCO-PEG4-maleimide stands out as a key reagent for researchers aiming to innovate in drug development and molecular biology.

Synonyms
Sulfo dibenzocyclooctyne-PEG4-maleimide
Purity
≥ 95% (HPLC)
Molecular Formula
C39H47N5O15S
Molecular Weight
825.89
Appearance
Grey amorphous solid
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Sulfo dibenzocyclooctyne-PEG4-maleimide
Purity
≥ 95% (HPLC)
Molecular Formula
C39H47N5O15S
Molecular Weight
825.89
Appearance
Grey amorphous solid
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Sulfo DBCO-PEG4-maleimide is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules like proteins or antibodies to surfaces or other molecules, enhancing the effectiveness of drug delivery systems.
  • Fluorescent Labeling: It is used to label proteins or nucleic acids with fluorescent tags, allowing researchers to visualize and track biological processes in real-time.
  • Targeted Drug Delivery: By conjugating drugs to specific targeting agents, it improves the precision of drug delivery, minimizing side effects and maximizing therapeutic effects in cancer treatment.
  • Diagnostics: The compound plays a crucial role in developing diagnostic assays, enabling the detection of diseases through specific biomolecular interactions.
  • Research in Cell Biology: It aids in studying cell interactions and signaling pathways, providing insights into cellular mechanisms and potential therapeutic targets.

Citations