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Catalog Number:
35052
CAS Number:
1378531-80-6
DBCO-PEG5-NHS ester
Purity:
≥ 95% (HPLC)
Synonym(s):
Dibenzocyclooctyne-PEG5-NHS ester
Documents
$140.20 /5MG
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Product Information

DBCO-PEG5-NHS ester is a versatile and highly functional chemical compound that plays a crucial role in bioconjugation and drug delivery applications. This compound features a unique structure that allows for efficient coupling with biomolecules, making it an ideal choice for researchers in the fields of biochemistry and molecular biology. Its polyethylene glycol (PEG) component enhances solubility and biocompatibility, which is essential for applications in therapeutic development and diagnostic imaging.

The DBCO-PEG5-NHS ester is particularly valuable in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapies, where precise attachment to proteins or nucleic acids is required. Its ability to form stable linkages with azide-functionalized molecules allows for selective labeling and tracking of biomolecules in complex biological systems. This compound is also used in the development of novel drug delivery systems, improving the pharmacokinetics and efficacy of therapeutic agents. With its unique properties and practical applications, DBCO-PEG5-NHS ester is an indispensable tool for researchers aiming to advance their work in drug development and molecular biology.

Synonyms
Dibenzocyclooctyne-PEG5-NHS ester
CAS Number
1378531-80-6
Purity
≥ 95% (HPLC)
Molecular Formula
C36H43N3O11
Molecular Weight
693.74
PubChem ID
86580458
Appearance
Viscous oil or amorphous solid
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Dibenzocyclooctyne-PEG5-NHS ester
CAS Number
1378531-80-6
Purity
≥ 95% (HPLC)
Molecular Formula
C36H43N3O11
Molecular Weight
693.74
PubChem ID
86580458
Appearance
Viscous oil or amorphous solid
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO-PEG5-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker for attaching biomolecules such as proteins, peptides, or antibodies to surfaces or other molecules, enhancing the development of targeted therapies.
  • Drug Delivery Systems: Its ability to form stable conjugates makes it ideal for creating advanced drug delivery systems that improve the efficacy and specificity of therapeutic agents in treating diseases.
  • Diagnostics: DBCO-PEG5-NHS ester is employed in the development of diagnostic tools, such as imaging agents, that allow for better visualization of biological processes in vivo.
  • Research in Material Science: This compound can be used to modify surfaces of materials, improving their properties for applications in sensors or biointerfaces, thus enhancing their performance in various industrial applications.
  • Vaccine Development: It plays a crucial role in the formulation of vaccines by facilitating the conjugation of antigens to carriers, which can enhance immune responses and provide better protection against diseases.

Citations