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Catalog Number:
35047
CAS Number:
1384870-47-6
DBCO-C6-NHS ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Dibenzocyclooctyne-C6-NHS ester
Documents
$119.90 /5MG
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Product Information

DBCO-C6-NHS ester is a versatile and highly functional compound widely utilized in bioconjugation and drug delivery applications. This compound features a unique structure that allows for efficient coupling with various biomolecules, making it an essential tool for researchers in the fields of biochemistry and molecular biology. Its ability to form stable linkages with amines and other nucleophiles enhances its utility in the development of targeted therapeutics and diagnostic agents.

Researchers have successfully employed DBCO-C6-NHS ester in the synthesis of antibody-drug conjugates (ADCs), which are pivotal in cancer therapy, as well as in the creation of fluorescent probes for imaging applications. The compound's stability and reactivity make it an ideal choice for creating complex biomolecular architectures, enabling advancements in personalized medicine and targeted delivery systems. With its robust performance and compatibility with various substrates, DBCO-C6-NHS ester stands out as a valuable asset for professionals seeking to innovate in drug development and molecular diagnostics.

Synonyms
Dibenzocyclooctyne-C6-NHS ester
CAS Number
1384870-47-6
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
MDL Number
MFCD22380763
PubChem ID
86580459
Appearance
White to grey solid
Conditions
Store at ≤ -10 °C, desiccate and shipped at ambient temperature
General Information
Synonyms
Dibenzocyclooctyne-C6-NHS ester
CAS Number
1384870-47-6
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
MDL Number
MFCD22380763
PubChem ID
86580459
Appearance
White to grey solid
Conditions
Store at ≤ -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

DBCO-C6-NHS ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules. Its reactive nature allows for precise and stable conjugation, making it ideal for developing targeted therapies.
  • Drug Delivery Systems: DBCO-C6-NHS ester can be used to create advanced drug delivery systems. By linking drugs to nanoparticles or liposomes, it enhances the efficacy and specificity of treatments, particularly in cancer therapy.
  • Fluorescent Labeling: Researchers use this compound to label biomolecules with fluorescent tags. This application is crucial in imaging techniques, allowing scientists to visualize cellular processes in real-time.
  • Diagnostics: In the field of diagnostics, DBCO-C6-NHS ester is utilized to develop assays that detect specific biomolecules. Its ability to form stable bonds aids in the creation of reliable diagnostic tools for diseases.
  • Material Science: This compound is also applied in the modification of surfaces for various materials. By enhancing surface properties, it can improve adhesion, biocompatibility, and functionality in biomedical devices.

Citations