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Catalog Number:
29778
CAS Number:
132622-65-2
(2S,4S)-Boc- 4-azido-pyrrolidine-2-carboxylic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-cis-Pro(4-azido)-OH
Documents
$86.23 /250MG
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Product Information

The compound (2S,4S)-Boc-4-azido-pyrrolidine-2-carboxylic acid is a versatile building block in organic synthesis, particularly valued in the fields of medicinal chemistry and bioconjugation. Its unique azido functional group allows for click chemistry applications, enabling researchers to easily attach this compound to various biomolecules, facilitating the development of targeted drug delivery systems and novel therapeutics. The Boc (tert-butyloxycarbonyl) protecting group enhances its stability and compatibility in various reaction conditions, making it an ideal candidate for peptide synthesis and modification.

This compound's chiral nature and specific stereochemistry also make it a valuable asset in asymmetric synthesis, where it can be employed to create complex molecular architectures with high selectivity. Its applications extend to the synthesis of bioactive compounds, where it can serve as a precursor for the development of inhibitors or other therapeutic agents. With its combination of stability, reactivity, and functional versatility, (2S,4S)-Boc-4-azido-pyrrolidine-2-carboxylic acid stands out as a crucial tool for researchers and industry professionals aiming to innovate in drug design and development.

Synonyms
Boc-cis-Pro(4-azido)-OH
CAS Number
132622-65-2
Purity
≥ 99% (HPLC)
Molecular Formula
C10H16N4O4
Molecular Weight
256.26
MDL Number
MFCD04115791
PubChem ID
14842620
Melting Point
76-83 ?C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -25 ± 2º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-cis-Pro(4-azido)-OH
CAS Number
132622-65-2
Purity
≥ 99% (HPLC)
Molecular Formula
C10H16N4O4
Molecular Weight
256.26
MDL Number
MFCD04115791
PubChem ID
14842620
Melting Point
76-83 ?C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -25 ± 2º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4S)-Boc-4-azido-pyrrolidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its azido group allows for click chemistry applications, facilitating the attachment of various functional groups.
  • Drug Development: The unique structure of this compound makes it valuable in the pharmaceutical industry for creating prodrugs or drug candidates that require specific bioactivation, enhancing their efficacy and reducing side effects.
  • Bioconjugation: Researchers use this chemical in bioconjugation processes, where it can be linked to biomolecules like proteins or antibodies. This application is crucial in developing targeted drug delivery systems and diagnostic tools.
  • Material Science: Its properties are exploited in the creation of functionalized polymers and materials, which can be used in various applications, including coatings and drug delivery systems, offering improved performance and stability.
  • Research in Chemical Biology: This compound is instrumental in studying biological processes and interactions at the molecular level, providing insights that can lead to advancements in understanding disease mechanisms and developing new therapies.

Citations