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Catalog Number:
45475
CAS Number:
53473-36-2
3-[4-(Trifluoromethyl)phenyl]propionic acid
Purity:
≥ 98% (Assay by titration)
Synonym(s):
4-(Trifluoromethyl)hydrocinnamic acid
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Product Information

3-[4-(Trifluoromethyl)phenyl]propionic acid is a versatile compound known for its unique trifluoromethyl group, which enhances its chemical stability and lipophilicity. This property makes it particularly valuable in the pharmaceutical industry, where it serves as a key intermediate in the synthesis of various bioactive molecules. Its ability to modulate biological activity allows researchers to explore its potential in drug development, especially in creating anti-inflammatory and analgesic agents. Additionally, this compound is utilized in agrochemicals, where its properties can improve the efficacy of herbicides and pesticides, contributing to more effective crop protection solutions.

The trifluoromethyl group not only increases the compound's metabolic stability but also enhances its interaction with biological targets, making it a preferred choice for medicinal chemists. Its applications extend to materials science, where it can be incorporated into polymers to impart desirable characteristics such as improved thermal stability and chemical resistance. Overall, 3-[4-(Trifluoromethyl)phenyl]propionic acid stands out for its multifaceted applications across various industries, making it a valuable addition to any research or production portfolio.

Synonyms
4-(Trifluoromethyl)hydrocinnamic acid
CAS Number
53473-36-2
Purity
≥ 98% (Assay by titration)
Molecular Formula
C10H9F3O2
Molecular Weight
218.18
MDL Number
MFCD00674032
PubChem ID
3588736
Melting Point
115 °C
Appearance
White to almost white powder to crystal
Conditions
Store at RT
General Information
Synonyms
4-(Trifluoromethyl)hydrocinnamic acid
CAS Number
53473-36-2
Purity
≥ 98% (Assay by titration)
Molecular Formula
C10H9F3O2
Molecular Weight
218.18
MDL Number
MFCD00674032
PubChem ID
3588736
Melting Point
115 °C
Appearance
White to almost white powder to crystal
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-[4-(Trifluoromethyl)phenyl]propionic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-inflammatory drugs. Its unique trifluoromethyl group enhances biological activity and selectivity.
  • Agricultural Chemicals: It is used in the formulation of agrochemicals, including herbicides and fungicides. The trifluoromethyl group contributes to improved efficacy and stability, making it valuable in crop protection.
  • Material Science: The compound is explored in the development of advanced materials, such as polymers and coatings. Its properties can enhance thermal stability and chemical resistance, which are crucial for industrial applications.
  • Analytical Chemistry: It is employed as a reagent in various analytical techniques, including chromatography and mass spectrometry. This aids in the detection and quantification of complex mixtures in environmental and biological samples.
  • Research in Organic Synthesis: The compound is a versatile building block in organic synthesis, allowing researchers to create a wide range of derivatives. Its unique structure provides opportunities for developing novel compounds with specific properties.

Citations