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Catalog Number:
45453
CAS Number:
454-92-2
3-(Trifluoromethyl)benzoic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
a,α,α-Trifluoro-m-toluic acid
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$20.00 /25G
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Product Information

3-(Trifluoromethyl)benzoic acid is a versatile compound recognized for its unique trifluoromethyl group, which enhances its chemical reactivity and solubility in various organic solvents. This property makes it an essential building block in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. Its ability to modify the electronic properties of molecules allows researchers to design compounds with improved efficacy and selectivity, particularly in drug development. Additionally, it serves as a valuable intermediate in the production of specialty chemicals, where its trifluoromethyl functionality can impart desirable characteristics such as increased lipophilicity and metabolic stability.

In the field of research, 3-(trifluoromethyl)benzoic acid is utilized in the development of novel compounds that exhibit enhanced biological activity. Its applications extend to the synthesis of fluorinated derivatives, which are often more potent than their non-fluorinated counterparts. This compound is particularly beneficial in medicinal chemistry, where it aids in the creation of targeted therapies and diagnostic agents. With its unique properties and broad applicability, 3-(trifluoromethyl)benzoic acid stands out as a crucial component for professionals seeking to innovate in chemical synthesis and product development.

Synonyms
a,α,α-Trifluoro-m-toluic acid
CAS Number
454-92-2
Purity
≥ 98% (HPLC)
Molecular Formula
C8H5F3O2
Molecular Weight
190.12
MDL Number
MFCD00002519
PubChem ID
9963
Melting Point
104 - 106 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
a,α,α-Trifluoro-m-toluic acid
CAS Number
454-92-2
Purity
≥ 98% (HPLC)
Molecular Formula
C8H5F3O2
Molecular Weight
190.12
MDL Number
MFCD00002519
PubChem ID
9963
Melting Point
104 - 106 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-(Trifluoromethyl)benzoic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, enhancing the efficacy and selectivity of drug candidates.
  • Agricultural Chemicals: It is used in the formulation of agrochemicals, particularly herbicides and fungicides, providing improved effectiveness against pests while minimizing environmental impact.
  • Material Science: The compound is incorporated into the development of advanced materials, such as polymers and coatings, which exhibit enhanced thermal stability and chemical resistance.
  • Analytical Chemistry: It acts as a standard in analytical methods, aiding in the accurate quantification of other compounds in complex mixtures, thus ensuring reliable results in research.
  • Fluorinated Compounds Research: The unique trifluoromethyl group allows for studies on the reactivity and properties of fluorinated compounds, contributing to advancements in organic synthesis and materials science.

Citations