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Catalog Number:
40248
CAS Number:
162101-25-9
2,6-Difluorophenylboronic acid
Purity:
98 - 105% (Assay by titration)
Synonym(s):
2,6-Difluorobenzeneboronic acid
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Product Information

2,6-Difluorophenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its unique ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceutical compounds. Its application extends to the synthesis of biologically active molecules, including those used in cancer research and the development of targeted therapies. The presence of fluorine atoms enhances its electronic properties, allowing for improved reactivity and selectivity in chemical reactions.

Researchers and industry professionals appreciate 2,6-Difluorophenylboronic acid for its role in Suzuki-Miyaura cross-coupling reactions, which are pivotal in constructing complex organic frameworks. This compound's stability and compatibility with various reaction conditions make it a preferred choice for synthesizing advanced materials and pharmaceuticals. Its unique characteristics not only streamline the synthesis process but also contribute to the efficiency and effectiveness of drug development, making it a valuable asset in both academic and industrial laboratories.

Synonyms
2,6-Difluorobenzeneboronic acid
CAS Number
162101-25-9
Purity
98 - 105% (Assay by titration)
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
MDL Number
MFCD00792436
PubChem ID
2734336
Melting Point
149 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2,6-Difluorobenzeneboronic acid
CAS Number
162101-25-9
Purity
98 - 105% (Assay by titration)
Molecular Formula
C6H5BF2O2
Molecular Weight
157.91
MDL Number
MFCD00792436
PubChem ID
2734336
Melting Point
149 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,6-Difluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is crucial in the synthesis of various pharmaceuticals, particularly in the development of targeted cancer therapies. Its ability to form stable complexes with certain biomolecules enhances drug efficacy.
  • Organic Synthesis: It serves as an important building block in organic chemistry, facilitating the creation of complex molecules through Suzuki coupling reactions. This method is favored for its efficiency and ability to produce high yields.
  • Material Science: The compound is used in the development of advanced materials, including polymers and coatings, where its unique properties contribute to improved performance and durability.
  • Bioconjugation: In biochemistry, it plays a role in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, which is essential for creating biosensors and diagnostic tools.
  • Environmental Applications: It is also explored in environmental chemistry for the detection and removal of pollutants, leveraging its reactivity to form complexes with harmful substances, thus aiding in remediation efforts.

Citations