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Catalog Number:
40145
CAS Number:
89466-08-0
2-Hydroxyphenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Hydroxybenzeneboronic acid
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Product Information

2-Hydroxyphenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to form reversible covalent bonds with diols, making it an essential reagent in the development of various pharmaceuticals and agrochemicals. Its unique properties enable it to serve as a key building block in the synthesis of complex organic molecules, particularly in the formation of boronate esters, which are crucial in cross-coupling reactions such as Suzuki-Miyaura coupling. Researchers appreciate its role in enhancing the efficiency of drug discovery processes, particularly in the design of targeted therapies.

In addition to its applications in organic synthesis, 2-Hydroxyphenylboronic acid has shown promise in the field of biosensors, where it can be employed for the detection of glucose and other biomolecules. Its selectivity and sensitivity make it a valuable tool in the development of diagnostic devices. Furthermore, the compound's compatibility with various solvents and reaction conditions allows for its use in diverse chemical environments, making it a preferred choice for researchers and industry professionals seeking reliable and efficient reagents.

Synonyms
2-Hydroxybenzeneboronic acid
CAS Number
89466-08-0
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H7BO3
Molecular Weight
137.93
MDL Number
MFCD01074581
PubChem ID
2773454
Melting Point
185 °C (dec.)
Appearance
White to light yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-Hydroxybenzeneboronic acid
CAS Number
89466-08-0
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H7BO3
Molecular Weight
137.93
MDL Number
MFCD01074581
PubChem ID
2773454
Melting Point
185 °C (dec.)
Appearance
White to light yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Hydroxyphenylboronic acid is widely utilized in research focused on:

  • Drug Development: This compound is crucial in the synthesis of various pharmaceuticals, particularly in creating compounds that target specific biological pathways, enhancing drug efficacy.
  • Bioconjugation: It serves as a versatile tool for attaching biomolecules, such as proteins and nucleic acids, to surfaces or other molecules, facilitating the development of biosensors and diagnostic tools.
  • Organic Synthesis: Used as a reagent in Suzuki-Miyaura cross-coupling reactions, it enables the formation of carbon-carbon bonds, which is essential in building complex organic molecules.
  • Material Science: This compound is employed in the development of smart materials, particularly in creating polymers that respond to environmental stimuli, useful in various applications from sensors to drug delivery systems.
  • Environmental Chemistry: It is utilized in the detection and removal of pollutants, particularly in water treatment processes, due to its ability to form complexes with heavy metals, aiding in environmental remediation efforts.

Citations