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Catalog Number:
40144
CAS Number:
5122-99-6
4-Iodophenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
4-Iodobenzeneboronic acid
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Product Information

4-Iodophenylboronic acid is a versatile compound widely recognized for its utility in organic synthesis and medicinal chemistry. This boronic acid derivative features a phenyl group substituted with an iodine atom, making it an essential building block in the development of pharmaceuticals and agrochemicals. Its unique reactivity allows for the formation of stable complexes with diols, which is particularly valuable in the synthesis of complex organic molecules. Researchers utilize 4-Iodophenylboronic acid in cross-coupling reactions, such as Suzuki-Miyaura coupling, to create carbon-carbon bonds, facilitating the construction of intricate molecular architectures.

In addition to its applications in organic synthesis, 4-Iodophenylboronic acid has shown promise in the field of targeted drug delivery and cancer therapy, where its ability to interact with specific biomolecules can be harnessed for therapeutic purposes. Its stability and ease of use make it a preferred choice for researchers looking to streamline their synthetic processes. With its broad range of applications, 4-Iodophenylboronic acid stands out as a crucial compound for advancing research and development in various chemical industries.

Synonyms
4-Iodobenzeneboronic acid
CAS Number
5122-99-6
Purity
95 - 105% (Assay by titration)
Molecular Formula
C6H6BIO2
Molecular Weight
247.83
MDL Number
MFCD01319014
PubChem ID
151254
Melting Point
286 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Iodobenzeneboronic acid
CAS Number
5122-99-6
Purity
95 - 105% (Assay by titration)
Molecular Formula
C6H6BIO2
Molecular Weight
247.83
MDL Number
MFCD01319014
PubChem ID
151254
Melting Point
286 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Iodophenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, allowing researchers to create complex molecules efficiently.
  • Cross-Coupling Reactions: It is commonly used in Suzuki-Miyaura coupling reactions, which are essential for forming carbon-carbon bonds in organic compounds, making it invaluable in materials science and drug development.
  • Bioconjugation: The boronic acid functionality allows for selective binding to diols, facilitating the development of targeted drug delivery systems and biomolecular probes in biochemistry.
  • Sensor Development: 4-Iodophenylboronic acid can be employed in the creation of chemical sensors for detecting sugars and other biomolecules, which is crucial in diagnostics and environmental monitoring.
  • Research in Medicinal Chemistry: Its unique properties enable the exploration of new therapeutic agents, particularly in cancer research, by modifying existing drug structures to enhance efficacy and reduce side effects.

Citations