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Catalog Number:
40135
CAS Number:
177171-16-3
3-(Trimethylsilyl)phenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
3-(Trimethylsilyl)benzeneboronic acid
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Product Information

3-(Trimethylsilyl)phenylboronic acid is a versatile organoboron compound that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it invaluable for the formation of carbon-carbon bonds. Its unique trimethylsilyl group enhances solubility and stability, allowing for efficient reactions under various conditions. Researchers and industry professionals utilize this compound in the development of pharmaceuticals, agrochemicals, and advanced materials, where precise molecular construction is essential.

Additionally, 3-(Trimethylsilyl)phenylboronic acid serves as a key intermediate in the synthesis of complex organic molecules, enabling the creation of diverse chemical libraries for drug discovery. Its compatibility with a range of functional groups and ease of handling make it an attractive choice for chemists seeking reliable and effective reagents. This compound not only streamlines synthetic pathways but also offers improved yields and selectivity compared to traditional boronic acids, positioning it as a preferred option in modern synthetic chemistry.

Synonyms
3-(Trimethylsilyl)benzeneboronic acid
CAS Number
177171-16-3
Purity
95 - 105% (Assay by titration)
Molecular Formula
C9H15BO2Si
Molecular Weight
194.11
MDL Number
MFCD03093884
PubChem ID
4577181
Melting Point
145 - 150 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-(Trimethylsilyl)benzeneboronic acid
CAS Number
177171-16-3
Purity
95 - 105% (Assay by titration)
Molecular Formula
C9H15BO2Si
Molecular Weight
194.11
MDL Number
MFCD03093884
PubChem ID
4577181
Melting Point
145 - 150 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-(Trimethylsilyl)phenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile building block in the synthesis of various organic molecules, particularly in the formation of carbon-carbon bonds through Suzuki coupling reactions, which are essential in creating complex pharmaceuticals and agrochemicals.
  • Drug Development: Its ability to form stable complexes with various biological targets makes it valuable in the pharmaceutical industry for the development of new drug candidates, particularly in targeting specific enzymes and receptors.
  • Material Science: The compound is used in the development of advanced materials, including polymers and nanomaterials, where its unique properties can enhance the performance and stability of the final products.
  • Analytical Chemistry: It plays a crucial role in analytical techniques, such as chromatography, where it can be used to improve the separation and detection of various compounds, aiding in quality control and research analysis.
  • Bioconjugation: This boronic acid derivative is effective in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems and diagnostic tools.

Citations