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Catalog Number:
40122
CAS Number:
182281-01-2
4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid
Purity:
98 - 105% (Assay by titration)
Synonym(s):
4-(Tetrahydro-2H-pyran-2-yloxy)benzeneboronic acid
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Product Information

4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block in the development of complex organic molecules. Its unique structure, featuring a tetrahydro-2H-pyran moiety, enhances its solubility and stability, which are critical attributes for various applications in pharmaceutical research and development.

Researchers and industry professionals can leverage this compound in the synthesis of biologically active compounds, including potential drug candidates and agrochemicals. Its effectiveness in forming carbon-carbon bonds allows for the efficient construction of diverse molecular architectures, streamlining the drug discovery process. Additionally, the compound's compatibility with various reaction conditions makes it a valuable tool in the synthesis of functionalized materials. With its practical applications and robust performance, 4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid stands out as a key reagent for advancing research in synthetic chemistry.

Synonyms
4-(Tetrahydro-2H-pyran-2-yloxy)benzeneboronic acid
CAS Number
182281-01-2
Purity
98 - 105% (Assay by titration)
Molecular Formula
C11H15BO4
Molecular Weight
222.05
MDL Number
MFCD02183525
PubChem ID
5017652
Melting Point
142 °C (Lit.)
Appearance
White to light yellow crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-(Tetrahydro-2H-pyran-2-yloxy)benzeneboronic acid
CAS Number
182281-01-2
Purity
98 - 105% (Assay by titration)
Molecular Formula
C11H15BO4
Molecular Weight
222.05
MDL Number
MFCD02183525
PubChem ID
5017652
Melting Point
142 °C (Lit.)
Appearance
White to light yellow crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-(Tetrahydro-2H-pyran-2-yloxy)phenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a crucial building block in the synthesis of complex organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Medicinal Chemistry: It is employed in drug discovery processes, especially for creating boron-containing compounds that can enhance the efficacy of therapeutic agents.
  • Bioconjugation: The unique properties of this boronic acid allow it to form stable bonds with biomolecules, making it valuable in the development of targeted drug delivery systems.
  • Material Science: It is used in the formulation of advanced materials, including polymers and nanomaterials, which benefit from its ability to modify surface properties.
  • Analytical Chemistry: This compound is utilized in various analytical techniques, such as chromatography, to improve the separation and detection of specific analytes.

Citations