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Catalog Number:
40104
CAS Number:
261621-12-9
3-(tert-Butyldimethylsilyloxy)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-(tert-Butyldimethylsilyloxy)benzeneboronic acid
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Product Information

3-(tert-Butyldimethylsilyloxy)phenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its unique tert-butyldimethylsilyloxy group enhances its stability and solubility, facilitating easier handling and application in various chemical processes.

Researchers and industry professionals appreciate this compound for its role in developing novel materials and drug candidates, especially in the field of targeted therapies. Its compatibility with a range of substrates allows for diverse applications, from the synthesis of biologically active compounds to the creation of advanced materials with tailored properties. The compound's robust performance in coupling reactions, combined with its favorable handling characteristics, positions it as a preferred choice for those looking to streamline their synthetic pathways while achieving high yields.

Synonyms
3-(tert-Butyldimethylsilyloxy)benzeneboronic acid
CAS Number
261621-12-9
Purity
97 - 105% (Assay by titration)
Molecular Formula
C12H21BO3Si
Molecular Weight
252.19
MDL Number
MFCD03701505
PubChem ID
3463029
Melting Point
91 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-(tert-Butyldimethylsilyloxy)benzeneboronic acid
CAS Number
261621-12-9
Purity
97 - 105% (Assay by titration)
Molecular Formula
C12H21BO3Si
Molecular Weight
252.19
MDL Number
MFCD03701505
PubChem ID
3463029
Melting Point
91 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-(tert-Butyldimethylsilyloxy)phenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile building block in the synthesis of complex organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Cross-Coupling Reactions: It is commonly used in Suzuki-Miyaura coupling reactions, allowing chemists to create carbon-carbon bonds efficiently, which is essential in the production of various organic compounds.
  • Drug Development: The compound's ability to form stable complexes with biomolecules makes it valuable in medicinal chemistry for designing new drug candidates targeting specific diseases.
  • Analytical Chemistry: It is employed as a reagent in various analytical techniques, enhancing the detection and quantification of phenolic compounds in environmental and food samples.
  • Material Science: This chemical is also explored in the development of functional materials, such as sensors and catalysts, due to its unique properties that improve performance compared to similar compounds.

Citations