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Catalog Number:
39901
CAS Number:
444120-95-0
2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity:
≥ 98% (GC)
Synonym(s):
2-(6-Fluoro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 6-Fluoropyridine-3-boronic acid pinacol ester
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$112.57 /1G
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Product Information

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a versatile compound that plays a significant role in organic synthesis and medicinal chemistry. This fluorinated pyridine derivative is particularly valued for its unique reactivity, which allows for the introduction of fluorine into various molecular frameworks. Its structure incorporates a dioxaborolane moiety, enhancing its utility in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is essential for the formation of carbon-carbon bonds in complex organic molecules. Researchers and industry professionals can leverage this compound for the development of pharmaceuticals, agrochemicals, and advanced materials, where precision in molecular design is crucial.

The compound's stability and compatibility with various reaction conditions make it an attractive choice for synthetic chemists looking to streamline their processes. Its ability to act as a versatile building block can facilitate the synthesis of novel compounds with potential applications in drug discovery and development. With its unique properties, 2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine stands out as a valuable tool for researchers aiming to innovate in the fields of chemistry and materials science.

Synonyms
2-(6-Fluoro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 6-Fluoropyridine-3-boronic acid pinacol ester
CAS Number
444120-95-0
Purity
≥ 98% (GC)
Molecular Formula
C11H15BFNO2
Molecular Weight
223.05
MDL Number
MFCD03412792
PubChem ID
12177222
Melting Point
29 - 33 ?C
Appearance
White to light yellow powder to lump
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-(6-Fluoro-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 6-Fluoropyridine-3-boronic acid pinacol ester
CAS Number
444120-95-0
Purity
≥ 98% (GC)
Molecular Formula
C11H15BFNO2
Molecular Weight
223.05
MDL Number
MFCD03412792
PubChem ID
12177222
Melting Point
29 - 33 ?C
Appearance
White to light yellow powder to lump
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer treatment.
  • Organic Synthesis: It is employed in organic synthesis as a versatile building block, allowing chemists to create complex molecules efficiently, which is crucial in both academic and industrial laboratories.
  • Material Science: The compound is used in the development of advanced materials, including polymers and coatings, which benefit from its unique chemical properties, enhancing durability and performance.
  • Agricultural Chemistry: It plays a role in the formulation of agrochemicals, contributing to the design of more effective pesticides and herbicides that are safer for the environment.
  • Fluorine Chemistry: This compound is significant in fluorine chemistry, enabling the introduction of fluorine into organic molecules, which can improve the biological activity and stability of drugs.

Citations