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Catalog Number:
39897
CAS Number:
452972-12-2
2-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity:
≥ 98% (GC)
Synonym(s):
2-(2-Bromo-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Bromo-3-pyridylboronic acid pinacol ester
Documents
$68.20 /1G
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Product Information

2-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This compound features a unique boron-containing moiety, which enhances its reactivity and makes it an excellent candidate for cross-coupling reactions, particularly in the development of complex organic molecules. Its distinctive structure allows for the introduction of bromine and boron functionalities, facilitating the formation of diverse carbon-carbon bonds. Researchers have successfully employed this compound in the synthesis of various pharmaceuticals and agrochemicals, showcasing its potential in drug discovery and development.

Additionally, the stability and ease of handling of 2-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine make it an attractive choice for both laboratory and industrial applications. Its ability to participate in palladium-catalyzed reactions opens up avenues for creating intricate molecular architectures, which are essential in the fields of materials science and nanotechnology. With its favorable properties and broad applicability, this compound is a valuable asset for researchers and industry professionals aiming to innovate and enhance their chemical processes.

Synonyms
2-(2-Bromo-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Bromo-3-pyridylboronic acid pinacol ester
CAS Number
452972-12-2
Purity
≥ 98% (GC)
Molecular Formula
C11H15BBrNO2
Molecular Weight
283.96
MDL Number
MFCD06798246
PubChem ID
12067061
Melting Point
28 ?C (Lit.)
Density
1.32 g/mL at 25 ?C
Appearance
White to off white crystalline powder
Conditions
Store at RT
General Information
Synonyms
2-(2-Bromo-3-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 2-Bromo-3-pyridylboronic acid pinacol ester
CAS Number
452972-12-2
Purity
≥ 98% (GC)
Molecular Formula
C11H15BBrNO2
Molecular Weight
283.96
MDL Number
MFCD06798246
PubChem ID
12067061
Melting Point
28 ?C (Lit.)
Density
1.32 g/mL at 25 ?C
Appearance
White to off white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile building block in the synthesis of complex organic molecules, particularly in the pharmaceutical industry, where it can facilitate the development of new drugs.
  • Cross-Coupling Reactions: It is employed in Suzuki-Miyaura cross-coupling reactions, allowing for the formation of carbon-carbon bonds, which is essential in creating diverse organic compounds.
  • Material Science: The compound can be used in the development of advanced materials, including polymers and coatings, due to its unique chemical properties that enhance material performance.
  • Fluorescent Probes: Researchers utilize it in the design of fluorescent probes for biological imaging, providing a means to visualize cellular processes in real-time.
  • Agricultural Chemistry: It finds applications in agrochemicals, aiding in the development of herbicides and pesticides that are more effective and environmentally friendly.

Citations