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Catalog Number:
40393
CAS Number:
458532-96-2
2-Chloropyridine-4-boronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
2-Chloro-4-pyridylboronic acid
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Product Information

2-Chloropyridine-4-boronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative features a chlorinated pyridine ring, making it an essential building block for the development of various pharmaceuticals and agrochemicals. Its unique reactivity allows for effective coupling reactions, particularly in Suzuki-Miyaura cross-coupling, which is crucial for forming carbon-carbon bonds. Researchers and industry professionals appreciate its role in synthesizing complex molecules, including biologically active compounds and advanced materials.

Additionally, 2-Chloropyridine-4-boronic acid exhibits excellent solubility in common organic solvents, enhancing its applicability in diverse reaction conditions. Its ability to participate in ligand exchange reactions further broadens its utility in catalysis and material science. This compound stands out for its efficiency in creating targeted compounds with high specificity, making it a preferred choice for chemists aiming to streamline their synthetic pathways. Whether in drug discovery or materials development, 2-Chloropyridine-4-boronic acid is a valuable asset for innovative research and industrial applications.

Synonyms
2-Chloro-4-pyridylboronic acid
CAS Number
458532-96-2
Purity
95 - 105% (Assay by titration)
Molecular Formula
C5H5BClNO2
Molecular Weight
157.36
MDL Number
MFCD03788416
PubChem ID
5151595
Melting Point
210 °C (Lit.)
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Chloro-4-pyridylboronic acid
CAS Number
458532-96-2
Purity
95 - 105% (Assay by titration)
Molecular Formula
C5H5BClNO2
Molecular Weight
157.36
MDL Number
MFCD03788416
PubChem ID
5151595
Melting Point
210 °C (Lit.)
Appearance
White to almost white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloropyridine-4-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key building block in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents and other therapeutic drugs. Its ability to form stable bonds with other molecules enhances drug efficacy.
  • Organic Synthesis: It is commonly used in Suzuki-Miyaura cross-coupling reactions, which are essential for creating complex organic compounds. This application is particularly valuable in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is utilized in the creation of advanced materials, including polymers and coatings. Its unique properties allow for improved durability and functionality in various applications.
  • Bioconjugation: Researchers leverage its boronic acid functionality for bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules. This is crucial in developing biosensors and targeted drug delivery systems.
  • Environmental Monitoring: It can be employed in the detection and quantification of certain pollutants due to its reactivity with specific environmental contaminants, making it useful in analytical chemistry and environmental science.

Citations