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Catalog Number:
40380
CAS Number:
872041-86-6
5-Fluoropyridine-3-boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Fluoro-3-pyridylboronic acid
Documents
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Product Information

5-Fluoropyridine-3-boronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is particularly valued for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the synthesis of various pharmaceuticals and agrochemicals. Its unique fluorine substitution enhances its reactivity and selectivity, allowing researchers to create complex molecular architectures with precision.

In addition to its applications in synthetic chemistry, 5-Fluoropyridine-3-boronic acid is also utilized in the development of targeted therapies, particularly in oncology, where it aids in the design of compounds that can selectively inhibit cancer cell growth. Its compatibility with various functional groups and ease of incorporation into larger molecules make it a preferred choice for chemists looking to innovate in drug discovery and development. With its proven track record in enhancing the efficiency of chemical reactions, this compound stands out as a valuable asset for both academic research and industrial applications.

Synonyms
5-Fluoro-3-pyridylboronic acid
CAS Number
872041-86-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H5BFNO2
Molecular Weight
140.91
MDL Number
MFCD07368243
PubChem ID
44717403
Melting Point
236 °C (Lit.)
Appearance
White to almost white crystalline powder
Conditions
Store at RT
General Information
Synonyms
5-Fluoro-3-pyridylboronic acid
CAS Number
872041-86-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H5BFNO2
Molecular Weight
140.91
MDL Number
MFCD07368243
PubChem ID
44717403
Melting Point
236 °C (Lit.)
Appearance
White to almost white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoropyridine-3-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer agents and antibiotics, enhancing the efficiency of drug discovery processes.
  • Organic Synthesis: It is commonly used in Suzuki-Miyaura cross-coupling reactions, allowing chemists to create complex organic molecules with precision, which is crucial in materials science and organic electronics.
  • Agricultural Chemicals: The compound plays a role in the formulation of agrochemicals, contributing to the development of effective herbicides and pesticides that improve crop yields while minimizing environmental impact.
  • Bioconjugation: It is utilized in bioconjugation techniques, aiding in the attachment of biomolecules to surfaces or other molecules, which is essential for creating targeted drug delivery systems and diagnostic tools.
  • Research in Fluorinated Compounds: As a fluorinated boronic acid, it is valuable in studies exploring the properties and applications of fluorinated compounds, which often exhibit unique characteristics beneficial in various chemical reactions.

Citations