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Catalog Number:
40369
CAS Number:
458532-97-3
3-Fluoropyridine-4-boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-Fluoro-4-pyridylboronic acid
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Product Information

3-Fluoropyridine-4-boronic acid is a versatile compound widely utilized in the fields of organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its role in Suzuki-Miyaura cross-coupling reactions, which are essential for the formation of carbon-carbon bonds. Its unique fluorine substituent enhances the reactivity and selectivity of the compound, making it an ideal building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Researchers appreciate its ability to facilitate the development of novel compounds with improved biological activity, thus expanding the potential for innovative drug discovery.

In addition to its applications in synthetic chemistry, 3-Fluoropyridine-4-boronic acid serves as a valuable intermediate in the preparation of various functionalized materials. Its compatibility with a range of reaction conditions allows for flexibility in experimental design, making it a preferred choice for chemists aiming to optimize their synthetic pathways. With its robust performance and significant contributions to advancing chemical research, this compound stands out as a key player in modern organic synthesis.

Synonyms
3-Fluoro-4-pyridylboronic acid
CAS Number
458532-97-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H5BFNO2
Molecular Weight
140.91
MDL Number
MFCD03788558
PubChem ID
2779353
Melting Point
220 °C (dec.)
Appearance
White to almost white crystalline powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
3-Fluoro-4-pyridylboronic acid
CAS Number
458532-97-3
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H5BFNO2
Molecular Weight
140.91
MDL Number
MFCD03788558
PubChem ID
2779353
Melting Point
220 °C (dec.)
Appearance
White to almost white crystalline powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-Fluoropyridine-4-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key building block in the synthesis of various pharmaceuticals, particularly in the development of anti-cancer drugs. Its unique structure allows for targeted modifications that enhance drug efficacy.
  • Organic Synthesis: It is commonly used in Suzuki-Miyaura cross-coupling reactions, which are essential for forming carbon-carbon bonds. This application is vital in creating complex organic molecules, making it invaluable in chemical research and development.
  • Agricultural Chemistry: The compound is explored for its potential in developing agrochemicals, including herbicides and pesticides. Its effectiveness in targeting specific biological pathways can lead to more efficient and environmentally friendly agricultural solutions.
  • Material Science: It is utilized in the synthesis of functional materials, such as polymers and nanomaterials. These materials can have applications in electronics, coatings, and sensors, offering enhanced performance characteristics.
  • Analytical Chemistry: 3-Fluoropyridine-4-boronic acid is also used in various analytical techniques, including chromatography and spectroscopy, to improve the detection and quantification of other compounds, providing researchers with more accurate results.

Citations