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Catalog Number:
40363
CAS Number:
136466-94-9
2,6-Difluoro-3-pyridineboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2,6-Difluoropyridine-3-boronic acid
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Product Information

2,6-Difluoro-3-pyridineboronic acid is a versatile chemical compound that plays a crucial role in various fields, particularly in medicinal chemistry and organic synthesis. This boronic acid derivative is recognized for its unique ability to form stable complexes with diols, making it an essential reagent in the development of pharmaceuticals and agrochemicals. Its fluorinated structure enhances its reactivity and selectivity, allowing researchers to utilize it in cross-coupling reactions, such as Suzuki-Miyaura coupling, which is pivotal for constructing complex organic molecules.

Moreover, 2,6-Difluoro-3-pyridineboronic acid has shown promise in the synthesis of biologically active compounds, contributing to the advancement of drug discovery and development. Its application extends to the creation of novel materials and catalysts, showcasing its adaptability in various chemical processes. With its favorable properties and broad applicability, this compound is an invaluable asset for researchers and industry professionals seeking efficient solutions in their projects.

Synonyms
2,6-Difluoropyridine-3-boronic acid
CAS Number
136466-94-9
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H4BF2NO2
Molecular Weight
158.9
MDL Number
MFCD03788245
PubChem ID
2762713
Melting Point
96 - 102 °C
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
2,6-Difluoropyridine-3-boronic acid
CAS Number
136466-94-9
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H4BF2NO2
Molecular Weight
158.9
MDL Number
MFCD03788245
PubChem ID
2762713
Melting Point
96 - 102 °C
Appearance
White to slightly yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,6-Difluoro-3-pyridineboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound plays a crucial role in the synthesis of various pharmaceuticals, particularly in creating targeted therapies for cancer treatment. Its boronic acid functionality allows for the formation of stable complexes with biomolecules.
  • Organic Synthesis: It is used as a building block in organic synthesis, facilitating the formation of carbon-carbon bonds through cross-coupling reactions. This is particularly valuable in the development of complex organic molecules.
  • Material Science: The compound is employed in the development of advanced materials, such as sensors and catalysts, due to its unique electronic properties and ability to form stable complexes.
  • Agricultural Chemistry: It has applications in the design of agrochemicals, helping to create more effective pesticides and herbicides that target specific pests while minimizing environmental impact.
  • Analytical Chemistry: This chemical is used in various analytical techniques, including chromatography and mass spectrometry, to enhance the detection and quantification of specific analytes in complex mixtures.

Citations