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Catalog Number:
40360
CAS Number:
868662-36-6
2-(Trifluoromethyl)pyridine-5-boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
6-(Trifluoromethyl)-3-pyridylboronic acid
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$112.57 /1G
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Product Information

2-(Trifluoromethyl)pyridine-5-boronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to participate in Suzuki-Miyaura coupling reactions, making it an essential building block for the synthesis of complex organic molecules, including pharmaceuticals and agrochemicals. Its trifluoromethyl group enhances lipophilicity, which can improve the bioavailability of drug candidates, thereby making it a crucial component in the development of new therapeutic agents.

Researchers and industry professionals appreciate this compound for its unique reactivity and stability, which allows for the formation of carbon-carbon bonds under mild conditions. Its application extends to the development of advanced materials and fine chemicals, where precision and efficiency are paramount. With its favorable properties, 2-(Trifluoromethyl)pyridine-5-boronic acid stands out as a key reagent for innovative research and development in various fields, including pharmaceuticals, agrochemicals, and materials science.

Synonyms
6-(Trifluoromethyl)-3-pyridylboronic acid
CAS Number
868662-36-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BF3NO2
Molecular Weight
190.92
MDL Number
MFCD07375381
PubChem ID
25134278
Appearance
White to light orange to green powder
Conditions
Store at RT
General Information
Synonyms
6-(Trifluoromethyl)-3-pyridylboronic acid
CAS Number
868662-36-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BF3NO2
Molecular Weight
190.92
MDL Number
MFCD07375381
PubChem ID
25134278
Appearance
White to light orange to green powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(Trifluoromethyl)pyridine-5-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in creating compounds that target specific biological pathways, enhancing drug efficacy.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki reactions, to form carbon-carbon bonds, which are essential in building complex organic molecules.
  • Agricultural Chemistry: This chemical is used in the development of agrochemicals, including herbicides and pesticides, providing effective solutions for crop protection and yield enhancement.
  • Material Science: It plays a role in the formulation of advanced materials, including polymers and coatings, due to its unique electronic properties, which can improve material performance.
  • Analytical Chemistry: The compound is utilized in various analytical techniques for detecting and quantifying other substances, making it valuable in quality control and environmental monitoring.

Citations