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Catalog Number:
40358
CAS Number:
762262-09-9
2-Methoxypyridine-4-boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
2-Methoxy-4-pyridylboronic acid
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Product Information

2-Methoxypyridine-4-boronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block for the formation of biaryl compounds, which are significant in pharmaceuticals and agrochemicals. Its unique methoxy group enhances its solubility and reactivity, allowing for more efficient coupling processes compared to other boronic acids.

Researchers and industry professionals can leverage 2-Methoxypyridine-4-boronic acid in the development of novel drug candidates and complex organic molecules. Its applications extend to the synthesis of various heterocycles and biologically active compounds, showcasing its importance in the pharmaceutical industry. Additionally, its compatibility with a range of functional groups makes it an attractive choice for chemists looking to streamline their synthetic pathways while achieving high yields.

Synonyms
2-Methoxy-4-pyridylboronic acid
CAS Number
762262-09-9
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H8BNO3
Molecular Weight
152.94
MDL Number
MFCD07368877
PubChem ID
23546919
Melting Point
210 - 218 °C
Appearance
White to light yellow crystalline powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
2-Methoxy-4-pyridylboronic acid
CAS Number
762262-09-9
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H8BNO3
Molecular Weight
152.94
MDL Number
MFCD07368877
PubChem ID
23546919
Melting Point
210 - 218 °C
Appearance
White to light yellow crystalline powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Methoxypyridine-4-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a crucial building block in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases, due to its ability to form stable complexes with biologically relevant molecules.
  • Organic Synthesis: It is employed in cross-coupling reactions, such as Suzuki-Miyaura coupling, which allows chemists to create complex organic molecules efficiently, making it invaluable in the production of agrochemicals and fine chemicals.
  • Material Science: The compound is used in the preparation of advanced materials, including polymers and nanomaterials, which have applications in electronics and coatings, enhancing performance characteristics like conductivity and durability.
  • Bioconjugation: Its boronic acid functionality enables the selective labeling of biomolecules, facilitating the study of protein interactions and cellular processes, which is essential in biochemistry and molecular biology research.
  • Environmental Chemistry: It can be utilized in the development of sensors for detecting pollutants, offering a practical solution for monitoring environmental health and safety, thus contributing to sustainable practices.

Citations