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Catalog Number:
40356
CAS Number:
937595-70-5
5-Chloro-2-fluoropyridine-3-boronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Chloro-2-fluoro-3-pyridylboronic acid
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Product Information

5-Chloro-2-fluoropyridine-3-boronic acid is a versatile boronic acid derivative that plays a crucial role in pharmaceutical and agrochemical research. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it an essential building block in the synthesis of complex organic molecules. Its unique combination of a chloro and a fluorine substituent on the pyridine ring enhances its reactivity and selectivity, allowing for the development of novel compounds with potential therapeutic applications. Researchers have utilized this compound in the design of targeted drug delivery systems and in the creation of new agrochemicals that improve crop yield and resistance.

The practical applications of 5-Chloro-2-fluoropyridine-3-boronic acid extend to various fields, including medicinal chemistry, where it aids in the synthesis of biologically active molecules. Its favorable properties, such as stability and compatibility with various reaction conditions, make it a preferred choice for chemists looking to streamline their synthetic processes. By incorporating this compound into their research, professionals can enhance the efficiency of their workflows and achieve more effective results in their projects.

Synonyms
5-Chloro-2-fluoro-3-pyridylboronic acid
CAS Number
937595-70-5
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H4BClFNO2
Molecular Weight
175.35
MDL Number
MFCD04972408
PubChem ID
24901779
Melting Point
126 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Chloro-2-fluoro-3-pyridylboronic acid
CAS Number
937595-70-5
Purity
97 - 105% (Assay by titration)
Molecular Formula
C5H4BClFNO2
Molecular Weight
175.35
MDL Number
MFCD04972408
PubChem ID
24901779
Melting Point
126 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Chloro-2-fluoropyridine-3-boronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound is crucial in the synthesis of various pharmaceuticals, particularly in the development of targeted therapies for cancer, due to its ability to form stable bonds with biological molecules.
  • Agrochemical Formulation: It serves as an important intermediate in the production of agrochemicals, enhancing crop protection products by improving their efficacy and reducing environmental impact.
  • Material Science: Used in the creation of advanced materials, this boronic acid derivative contributes to the development of polymers and composites with enhanced properties, such as improved thermal stability and mechanical strength.
  • Organic Synthesis: It plays a significant role in cross-coupling reactions, which are essential for constructing complex organic molecules, making it a valuable tool for chemists in both academic and industrial settings.
  • Diagnostic Applications: The compound is being explored for use in diagnostic assays, particularly in the detection of biomarkers, thereby aiding in early disease diagnosis and monitoring.

Citations